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Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 160, 页码: 496-505
作者:  Wang, Jun;  Wang, Lijun;  Zhang, Shuhong;  Fan, Junting;  Yang, Hui
收藏  |  浏览/下载:56/0  |  提交时间:2020/10/26
Inhibitory Effect of Metalloproteinase Inhibitors on Skin Cell Inflammation Induced by Jellyfish Nemopilema nomurai Nematocyst Venom 期刊论文
TOXINS, 2019, 卷号: 11, 期号: 3, 页码: 12
作者:  Li, Aoyu;  Yu, Huahua;  Li, Rongfeng;  Liu, Song;  Xing, Ronge
收藏  |  浏览/下载:66/0  |  提交时间:2019/08/28
Design, synthesis and preliminary bioactivity evaluations of 8-hydroxyquinoline derivatives as matrix metalloproteinase (MMP) inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 181
作者:  Chen, Chen;  Yang, Xinying;  Fang, Hao;  Hou, Xuben
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/11
Viridicatol and viridicatin isolated from a shark-gill-derived fungus Penicillium polonicum AP2T1 as MMP-2 and MMP-9 inhibitors in HT1080 cells by MAPKs signaling pathway and docking studies 期刊论文
2019, 卷号: 28, 期号: 7, 页码: 1039
作者:  Liang, Peng[1];  Zhang, Yuan Yuan[1];  Yang, Ping[2];  Grond, Stephanie[3];  Zhang, Yi[2,4]
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/26
Synthesis and biological evaluation of novel benzofuroxan-based pyrrolidine hydroxamates as matrix metalloproteinase inhibitors with nitric oxide releasing activity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 15, 页码: 4363-4374
作者:  Zhang, Hao;  Wang, Xuejian;  Mao, Jing;  Huang, Yongxue;  Xu, Wenfang
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/11
Structural analysis and insight into novel MMP-13 inhibitors from natural chemiome as disease-modifying osteoarthritis drugs 期刊论文
2018, 卷号: 17, 期号: 11, 页码: 2255
作者:  Xiang, Yang[1];  Li, Yuanhui[1];  Ling, Zhirong[1];  Cheng, Yanzi[2]
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/13
Gelatinase inhibitors: a patent review (2011-2017) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2018, 卷号: 28, 期号: 1, 页码: 31-46
作者:  Li, Xun
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/11
Selective MMP-13 inhibitors: promising agents for the therapy of Osteoarthritis. 期刊论文
Current medicinal chemistry, 2018
作者:  Wan Yichao;  Li Wei;  Liao Zhipeng;  Yan Mi;  Chen Xuwang
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/26
Expression of MMP-2 and TIMP-1 during rapid maxillary expansion in rats 期刊论文
ARCHIVES OF ORAL BIOLOGY, 2017, 卷号: 76
作者:  Chen, Jianwei;  Zhou, Jing;  Li, Fan;  Sun, Jianfeng;  Li, Guifeng
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/04
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms 期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:  Peng, Mei*;  Darko, Kwame Oteng;  Tao, Ting;  Huang, Yanjun;  Su, Qiongli
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/03
AIs  aromatase inhibitors  AMPK  Adenosine Monophosphate-Activated Protein Kinase  AR  androgen  ATM  Ataxia Telangiectasia Mutated  ATP  Adenosine Triphosphate  BCSS  breast cancer specific survival  CK-MB  Creatine Kinase-MB  CREB1  cAMP Response Element-Binding Protein 1  CSC  cancer stem cell  DFS  disease-free survival  DHFU  dihydrofluorouracil  DPD  dihydropyrimidine dehydrogenase  EpCAM  Epithelial Cell Adhesion Molecule  ER  estrogen  ERCC1  excision repair cross-complementary 1  ERK  extracellular signal-regulated kinases  EZH2  enhancer of zeste homolog 2  FdUMP  fluorodeoxyuridine monophosphate  FdUTP  fluorodeoxyuridine triphosphate  FHC  ferritin heavy chain  FUTP  fluorouridine triphosphate  HbA1C  hemoglobin A1c  HER  Human Epidermal Growth Factor Receptor  HIF-1α  hypoxia-inducible factor-1α  HK  hexokinase  IGF1R  insulin growth factor 1 receptor  LDH  lactate dehydrogenase  MDA  Muscular Dystrophy Association  MMP  Matrix Metallopeptidase  MRP1  multidrug resistance-associated protein 1  mTOR  mammalian target of rapamycin  MTX  methotrexate  NCCN  National Comprehensive Cancer Network  OS  overall survival  pCR  Pathologic Complete Response  PDGFR  platelet-derived growth factor receptors  PFS  progression-free survival  PKA  protein kinase A  PR  progesterone receptor  RFS  relapse-free survival  SOD  superoxide dismutase  TAM  tamoxifen  TCA  tricarboxlic acid  TS  thymidylate synthase  Combination  Mechanisms  Metformin  Chemotherapeutic drugs  


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