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Oridonin inhibits DNMT3A R882 mutation-driven clonal hematopoiesis and leukemia by inducing apoptosis and necroptosis 期刊论文
CELL DEATH DISCOVERY, 2021, 卷号: 7, 期号: 1, 页码: 12
作者:  Liao, Min;  Dong, Qiongye;  Chen, Ruiqing;  Xu, Liqian;  Jiang, Yuxuan
收藏  |  浏览/下载:33/0  |  提交时间:2021/12/01
CAMKs support development of acute myeloid leukemia 期刊论文
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2018, 卷号: 11, 页码: 30
作者:  Kang, Xunlei;  Cui, Changhao;  Wang, Chen;  Wu, Guojin;  Chen, Heyu
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/02
Niche TWIST1 is critical for maintaining normal hematopoiesis and impeding leukemia progression 期刊论文
2018, 卷号: 103, 期号: 12, 页码: 1969-1979
作者:  Liu, Xiaoyan;  Ma, Yanping;  Li, Rongrong;  Guo, Dan;  Wang, Nan
收藏  |  浏览/下载:7/0  |  提交时间:2020/01/03
EpCAM Inhibition Sensitizes Chemoresistant Leukemia to Immune Surveillance 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 2, 页码: 482-493
作者:  Zheng, Xiaohu;  Fan, Xiaolei;  Fu, Binqing;  Zheng, Meijuan;  Zhang, Aimei
收藏  |  浏览/下载:38/0  |  提交时间:2018/07/04
Systematic computation with functional gene-sets among leukemic and hematopoietic stem cells reveals a favorable prognostic signature for acute myeloid leukemia 期刊论文
BMC BIOINFORMATICS, 2015, 卷号: 16, 期号: 1, 页码: 97-97
作者:  Yang, XH;  Li, MY;  Wang, B;  Zhu, WQ;  Desgardin, A
收藏  |  浏览/下载:26/0  |  提交时间:2015/07/22
Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation 期刊论文
Pharmacology and Therapeutics, 2015, 卷号: 151, 页码: 121-140
作者:  Liu, Ke;  Liu, Yanli;  Lau, Johnathan L;  Min, Jinrong*
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/23
Histone demethylation  DNA methylation  Inhibitor  Chemical probe  Drug discovery  LSD  lysine-specific histone demethylase  HDAC  histone deacetylase  REST  REST corepressor  DNMT  DNA methyltransferase  MAO  monoamine oxidase  AML  acute myeloid leukemia  KDM  lysine-specific demethylase  MLL  mixed lineage leukemia  FAD  flavin adenine dinucleotide  PCPA  trans-2-phenylcyclopropylamine  2,4-PDCA  2, 4-pyridinedicarboxylic acid  PHD  plant homeobox domain  SCLC  small cell lung cancer  JHDMs  JmjC-domain-containing histone demethylases  NOG  N-oxalylglycine  IOX1  5-carboxy-8-hydroxyquinoline  MDS  myelodysplastic syndrome  2-OG, 2-oxoglutarate or  α-ketoglutarate  G9a  euchromatic histone-lysine N-methyltransferase 2  CoREST complex  restin corepressor complex  SAH  S-adenosyl-l-homocysteine  l  SWI complex  ATP dependent chromatin remodeling complexes  Pan-Histone Demethylase Inhibitor  the inhibitor can simultaneously inhibit both LSDs and JHDMs  LSC colony  leukemic stem cell colony  Pan JmjC domain-containing demethylase inhibitor  the inhibitor can simultaneously inhibit all the members of JHDMs  E2F1  E2F transcription factor 1  E2F2  E2F transcription factor 2  RCC  renal cell carcinoma  
Leukemic marrow infiltration reveals a novel role for Egr3 as a potent inhibitor of normal hematopoietic stem cell proliferation 期刊论文
2015, 卷号: 126, 期号: 11, 页码: 1302-1313
作者:  Cheng, Hui;  Hao, Sha;  Liu, Yanfeng;  Pang, Yakun;  Ma, Shihui
收藏  |  浏览/下载:2/0  |  提交时间:2020/01/13
N-Cadherin and Tie2 positive CD34(+) CD38(-)CD123(+) leukemic stem cell populations can develop acute myeloid leukemia more effectively in NOD/SCID mice 期刊论文
2014, 卷号: 38, 期号: 5, 页码: 632-637
作者:  Qiu, Shaowei;  Jia, Yujiao;  Xing, Haiyan;  Yu, Tengteng;  Yu, Jing
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/13
Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment 期刊论文
2013, 卷号: 12, 期号: 2, 页码: 322-331
作者:  Tian, Chen;  Zheng, Guoguang;  Cao, Zhipan;  Li, Qiao;  Ju, Zhenyu
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/13
Distinct Effects of SCF and Hes1 On Normal Hematopoietic Stem and Progenitor Cells During Leukemic Cell Expansion in a T-ALL Mouse Model 期刊论文
2012, 卷号: 120, 期号: 21
作者:  Tian, Chen;  Cao, Zhipan;  Li, Qiao;  Wang, Jinhong;  Ju, Zhenyu
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/13


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