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Exploring cell-specific miRNA regulation with single-cell miRNA-mRNA co-sequencing data
期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22
作者:
Zhang, Junpeng
;
Liu, Lin
;
Xu, Taosheng
;
Zhang, Wu
;
Zhao, Chunwen
收藏
  |  
浏览/下载:149/0
  |  
提交时间:2022/01/10
miRNA
mRNA
Single-cell miRNA-mRNA co-sequencing
Pseudo-cell interpolation
Cell-specific miRNA regulation
Single-cell clustering analysis
Cell-cell crosstalk
Chronic myelogenous leukemia
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML)
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897
作者:
Lu, Tingting
;
Cao, Jiangyan
;
Zou, Fengming
;
Li, Xixiang
;
Wang, Aoli
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/04/26
BCR-ABL
ABL mutants
Chronic myeloid leukemia
Kinase inhibitor
Imatinib resistance
Heat shock transcription factor 1 regulates the fetal gamma-globin expression in a stress-dependent and independent manner during erythroid differentiation
期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 10
作者:
Gao, Jie
;
Liu, Jinhua
;
Zhang, Lingling
;
Zhang, Yingnan
;
Guo, Qing
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/08/24
HSF1
beta-globin genes
Transcription regulation
Stress
Xanthohumol, a Prenylated Flavonoid from Hops, Induces Caspase-Dependent Degradation of Oncoprotein BCR-ABL in K562 Cells
期刊论文
ANTIOXIDANTS, 2019, 卷号: 8, 期号: 9
作者:
Lu, Xuxiu
;
Geng, Jiajia
;
Zhang, Jinman
;
Miao, Jinlai
;
Liu, Ming
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  |  
浏览/下载:30/0
  |  
提交时间:2019/10/29
K562
xanthohumol
BCR-ABL
degradation
autophagy
caspase
Xanthohumol, a Prenylated Flavonoid from Hops, Induces Caspase-Dependent Degradation of Oncoprotein BCR-ABL in K562 Cells
期刊论文
ANTIOXIDANTS, 2019, 卷号: 8, 期号: 9
作者:
Lu, Xuxiu
;
Geng, Jiajia
;
Zhang, Jinman
;
Miao, Jinlai
;
Liu, Ming
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/10/29
K562
xanthohumol
BCR-ABL
degradation
autophagy
caspase
Learning common and specific patterns from data of multiple interrelated biological scenarios with matrix factorization
期刊论文
NUCLEIC ACIDS RESEARCH, 2019, 卷号: 47, 期号: 13, 页码: 6606-6617
作者:
Zhang, Lihua
;
Zhang, Shihua
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  |  
浏览/下载:48/0
  |  
提交时间:2020/01/10
(+/-) Cochlearoids N-P: three pairs of phenolic meroterpenoids from the fungus Ganoderma cochlear and their bioactivities
期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 卷号: 21, 期号: 6, 页码: 542-550
作者:
Qin, Fu-Ying
;
Yan, Yong-Ming
;
Tu, Zheng-Chao
;
Cheng, Yong-Xian
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  |  
浏览/下载:56/0
  |  
提交时间:2019/06/24
Ganoderma cochlear
meroterpenoids
BRD4
cytotoxic activity
antibacterial activity
Phenolic compounds from the insect Blaps japanensis with inhibitory activities towards cancer cells, COX-2, ROCK1 and JAK3
期刊论文
TETRAHEDRON, 2019, 卷号: 75, 期号: 8, 页码: 1029-1033
作者:
Yan, Yong-Ming
;
Zhu, Hong-Jie
;
Zhou, Feng-Jiao
;
Tu, Zheng-Chao
;
Cheng, Yong-Xian
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2019/03/25
Insect
Blaps japanensis
Phenolic compounds
Cytotoxicity
COX-2
ROCK1
JAK3
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:
Lin, Xin
;
Tian, Dongsong
;
Fu, Yanhui
;
Li, Yanan
;
Huang, Liejun
收藏
  |  
浏览/下载:143/0
  |  
提交时间:2019/03/18
Polycyclic polyprenylated acylphloroglucinol
Chemical transformation
Cytotoxicity
Cell apoptosis
Cell cycle arrest
Levistolide A synergistically enhances doxorubicin-induced apoptosis of k562/dox cells by decreasing MDR1 expression through the ubiquitin pathway
期刊论文
ONCOLOGY REPORTS, 2019, 卷号: 41, 页码: 1198-1208
作者:
Ding, Yuanyuan
;
Niu, Weibo
;
Zhang, Tao
;
Wang, Jue
;
Cao, Jiao
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/11/19
MDR1
levistolide A
multidrug resistance
chemotherapeutic drugs
downregulation
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