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浏览/检索结果: 共3条，第1-3条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the kappa-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 3, 页码: 1575-1584 作者:  An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Zhou, Shuangyan;  Shi, Danfeng 收藏  |  浏览/下载：57/0  |  提交时间：2019/11/10 kappa-opioid receptor  Gaussian accelerated molecular dynamics simulation  agonist  antagonist  conformational change   Computational insights into the subtype selectivity and "message-address-efficacy" mechanisms of opioid receptors through JDTic binding and unbinding 期刊论文 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 3, 页码: 482-491 作者:  Cheng, Jian-xin;  Cheng, Tao;  Li, Wei-hua;  Liu, Gui-xia;  Zhu, Wei-liang 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 G-protein-coupled receptors  opioid receptors  subtype selectivity  molecular dynamics  "message-address-efficacy" hypothesis  JDTic   Computational insights into different inhibition modes of the kappa-opioid receptor with antagonists LY2456302 and JDTic 期刊论文 RSC ADVANCES, 2016, 卷号: 6, 期号: 17, 页码: 13626-13635 作者:  Cheng, Jianxin;  Li, Weihua;  Liu, Guixia;  Zhu, Weiliang;  Tang, Yun 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08