CORC

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CORC

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Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu
收藏  |  浏览/下载：37/0  |  提交时间：2021/12/01
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui
收藏  |  浏览/下载：85/0  |  提交时间：2021/11/04
Structural insights into ligand recognition and activation of the melanocortin-4 receptor 期刊论文
CELL RESEARCH, 2021, 页码: 13
作者:  Zhang, Huibing;  Chen, Li-Nan;  Yang, Dehua;  Mao, Chunyou;  Shen, Qingya
收藏  |  浏览/下载：31/0  |  提交时间：2021/11/04
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li
收藏  |  浏览/下载：110/0  |  提交时间：2021/05/24
Structural basis for ligand recognition of the neuropeptide Y Y-2 receptor 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 9
作者:  Tang, Tingting;  Hartig, Christin;  Chen, Qiuru;  Zhao, Wenli;  Kaiser, Anette
收藏  |  浏览/下载：39/0  |  提交时间：2021/05/24
TREK Channel Family Activator with a Well-Defined Structure-Activation Relationship for Pain and Neurogenic Inflammation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 7, 页码: 3665-3677
作者:  Qiu, Yunguang;  Huang, Lu;  Fu, Jie;  Han, Chenxia;  Fang, Jing
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01
Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14
作者:  Chen, Yun;  Bai, Gang;  Ning, Yi;  Cai, Shi;  Zhang, Tao
收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01
Structural basis of Fusarium myosin I inhibition by phenamacril 期刊论文
PLOS PATHOGENS, 2020, 卷号: 16, 期号: 3, 页码: 23
作者:  Zhou, Yuxin;  Zhou, X. Edward;  Gong, Yuanping;  Zhu, Yuanye;  Cao, Xiaoman
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01
A Novel G Protein-Biased and Subtype-Selective Agonist for a G Protein-Coupled Receptor Discovered from Screening Herbal Extracts 期刊论文
ACS CENTRAL SCIENCE, 2020, 卷号: 6, 期号: 2, 页码: 213-225
作者:  Zhang, Bingjie;  Zhao, Simeng;  Yang, Dehua;  Wu, Yiran;  Xin, Ye
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/01
Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
作者:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping
收藏  |  浏览/下载：29/0  |  提交时间：2019/11/27

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