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北京大学 [14]
上海药物研究所 [8]
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复旦大学上海医学院 [7]
山东大学 [5]
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期刊论文 [87]
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Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:
Elksnis, Andris
;
Schiffer, Tomas A.
;
Palm, Fredrik
;
Wang, Yun
;
Cen, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:
Jiang, Bo
;
Luo, Jiao
;
Guo, Shuju
;
Wang, Lijun
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  |  
浏览/下载:32/0
  |  
提交时间:2021/05/11
Type 2 diabetes mellitus
Protein tyrosine phosphatase 1B inhibitors
Thiazolidinedione
Insulin signaling
Anti-diabetic activities
The phosphatidylserine flippase beta-subunit Tmem30a is essential for normal insulin maturation and secretion
期刊论文
MOLECULAR THERAPY, 2021, 卷号: 29, 期号: 9
作者:
Yang, Yeming
;
Sun, Kuanxiang
;
Liu, Wenjing
;
Li, Xiao
;
Tian, Wanli
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/11/18
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:
Luo, Jiao
;
Zheng, Meiling
;
Jiang, Bo
;
Li, Chao
;
Guo, Shuju
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2020/09/29
bromophenol
PTP1B inhibitor
selectivity
cell permeability
oral bioavailability
Oligomannuronate prevents mitochondrial dysfunction induced by IAPP in RINm5F islet cells by inhibition of JNK activation and cell apoptosis
期刊论文
Chinese Medicine, 2020, 卷号: 15, 期号: 1, 页码: 1-12.
作者:
Xi Liu
;
Qiong Li
;
Xiaolei Cheng
;
Zhichun Liu
;
Xiaoliang Zhao
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/03/10
Oligomannuronate
Type 2 diabetes
Islet amyloid polypeptide
JNK activation
Mitochondrial dysfunction
RINm5F cells
Engineering human islet organoids from iPSCs using an organ-on-chip platform
期刊论文
LAB ON A CHIP, 2019, 卷号: 19, 期号: 6, 页码: 948-958
作者:
Deng, Pengwei
;
Tao, Tingting
;
Wang, Yaqing
;
Chen, Wenwen
;
Li, Zhongyu
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/06/20
Engineering human islet organoids from ipscs using an organ-on-chip platform
期刊论文
Lab on a chip, 2019, 卷号: 19, 期号: 6, 页码: 948-958
作者:
Tao, Tingting
;
Wang, Yaqing
;
Chen, Wenwen
;
Li, Zhongyu
;
Su, Wentao
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  |  
浏览/下载:86/0
  |  
提交时间:2019/05/08
CLINICAL STUDY ON THE TREATMENT OF ISLET B CELL FAILURE TYPE 2 DIABETES WITH INSULIN LYSINE COMBINED WITH INSULIN GLULISINE
期刊论文
ACTA MEDICA MEDITERRANEA, 2019, 卷号: 35, 期号: 4
作者:
Liu, Shufang
;
Kong, Fanling
;
Wang, Yi
;
Zhang, Xiaoyong
;
Gao, Xiaoli
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
Insulin glulisine
insulin glargine
islet beta cell failure type 2 diabetes
Dual effect of peg-pe micelle over the oligomerization and fibrillation of human islet amyloid polypeptide
期刊论文
Scientific reports, 2018, 卷号: 8, 页码: 12
作者:
Fang, Xiaocui
;
Yousaf, Maryam
;
Huang, Qunxing
;
Yang, Yanlian
;
Wang, Chen
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/04/23
Clinical and Physiological Characterization of Elevated Plasma Glucagon-Like Peptide-1 Levels (Hyperglipemia) in a Dipeptidyl Peptidase IV Mutation Carrier
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9
作者:
Zhao, Dandan
;
Zhao, Shaoqian
;
Wang, Xiao
;
Su, Mingbo
;
Liu, Wen
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/01/08
dipeptidyl peptidase IV
glucagon-like peptide-1
beta-cell function
type 2 diabetes
incretin effect
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