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科研机构
上海药物研究所 [8]
成都生物研究所 [1]
四川大学 [1]
暨南大学 [1]
中国医学科学院 北京... [1]
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期刊论文 [12]
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2021 [1]
2020 [2]
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2018 [3]
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Chemistry ... [1]
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The ups, downs and new trends of IDO1 inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 12
作者:
Chen, Shulun
;
Tan, Jing
;
Zhang, Ao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/08/17
Immunotherapy
Cancer
Indoleamine 2,3-dioxygenase
Tryptophan 2,3-dioxygenase
Inhibitors
Checkpoint Inhibitor
Discovery and characterization of natural products as novel indoleamine 2,3-dioxygenase 1 inhibitors through high-throughput screening
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 423-431
作者:
Guo, Wei
;
Yao, Sheng
;
Sun, Pu
;
Yang, Tian-biao
;
Tang, Chun-ping
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2020/07/01
indoleamine 2
3-dioxygenase 1 inhibitor
natural product library
high-throughput fluorescence-based screening
discoveryandcharacterizationofnaturalproductsasnovelindoleamine23dioxygenase1inhibitorsthroughhighthroughputscreening
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 423
作者:
Guo Wei
;
Yao Sheng
;
Sun Pu
;
Yang Tianbiao
;
Tang Chunping
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/07/01
indoleamine 2
3-dioxygenase 1 inhibitor
natural product library
high-throughput fluorescence-based screening
Design, synthesis and antitumor study of a series of N-Cyclic sulfamoylaminoethyl substituted 1,2,5-oxadiazol-3-amines as new indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 179, 页码: 38-55
作者:
Chen, Shulun
;
Guo, Wei
;
Liu, Xiaohua
;
Sun, Pu
;
Wang, Yi
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Indoleamine 2,3-dioxygenase
Immunotherapy
Oxadiazole
PD-1
Life span
Self-Amplified Drug Delivery with Light-Inducible Nanocargoes to Enhance Cancer Immunotherapy
期刊论文
ADVANCED MATERIALS, 2019, 页码: 10
作者:
Feng, Bing
;
Hou, Bo
;
Xu, Zhiai
;
Saeed, Madiha
;
Yu, Haijun
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  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
cancer metastasis
chemoimmunotherapy
immunogenic cell death
immunosuppressive tumor microenvironment
self-amplification
Inhibition of the BET family reduces its new target gene IDO1 expression and the production of L-kynurenine
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 13
作者:
Tian, Chang-Qing
;
Chen, Lin
;
Chen, Hua-Dong
;
Huan, Xia-Juan
;
Hu, Jian-Ping
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Small-Molecule Immuno-Oncology Therapy: Advances, Challenges and New Directions
期刊论文
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 3, 页码: 180-185
作者:
Chen, Shulun
;
Song, Zilan
;
Zhang, Ao
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  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
4,6-Substituted-1 H-Indazoles as potent IDO1/TDO dual inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 6, 页码: 1087-1098
作者:
Yang, Lingling
;
Chen, Yang
;
He, Junlin
;
Njoya, Emmanuel Mfotie
;
Chen, Jianjun
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2021/11/04
Indoleamine 2,3-dioxygenase 1 (IDO1)
Tryptophan 2,3-dioxygenase (TDO)
1H-Indazoles
Dual inhibitor
Cancer immunotherapy
Antitumor activity
Discovery of Novel Inhibitors of Indoleamine 2,3-Dioxygenase 1 Through Structure-Based Virtual Screening
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Zhang, Guoqing
;
Xing, Jing
;
Wang, Yulan
;
Wang, Lihao
;
Ye, Yan
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
indoleamine 2, 3-dioxygense
IDO1 inhibitor
virtual screening
molecular docking
hit expansion
A highly potent and selective inhibitor Roxyl-WL targeting IDO1 promotes immune response against melanoma
期刊论文
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018, 卷号: Vol.33 No.1, 页码: 1089-1094
作者:
Xu, GW
;
Wang, TQ
;
Li, YT
;
Huang, Z
;
Wang, X
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/02/25
IDO1
inhibitor
melanoma
immunotherapy
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