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Discovery of dihydrooxazolo[2,3-a]isoquinoliniums as highly specific inhibitors of hCE2
期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 61, 页码: 35904-35912
作者:
Ding, Lixia
;
Wang, Lu
;
Zou, Kun
;
Li, Bo
;
Song, Yunqing
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 8, 页码: 843-853
作者:
Li, Xiuli
;
Sun, Jingchao
;
Guo, Zitao
;
Zhong, Dafang
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Recent progress and challenges in screening and characterization of UGT1A1 inhibitors
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 258-278
作者:
Finel, Moshe
;
Lv, Xia
;
Xia, Yangliu
;
Wu, Jingjing
;
Ge, Guangbo
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2019/06/20
UGT1A1 inhibitors
Drug/herbdrug interactions
Probe substrates
High-throughput screening
Recent progress and challenges in screening and characterization of ugt1a1 inhibitors
期刊论文
Acta pharmaceutica sinica b, 2019, 卷号: 9, 期号: 2, 页码: 258-278
作者:
Lv, Xia
;
Xia, Yangliu
;
Finel, Moshe
;
Wu, Jingjing
;
Ge, Guangbo
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2019/05/08
Ugt1a1 inhibitors
Drug/herbdrug interactions
Probe substrates
High-throughput screening
Discovery of a highly specific and efficacious inhibitor of human carboxylesterase 2 by large-scale screening
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 137
作者:
Song, Yun-Qing
;
Guan, Xiao-Qing
;
Weng, Zi-Miao
;
Wang, Ya-Qiao
;
Chen, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/05
Glabridin
Human carboxylesterase 2 (CES2A)
Specific inhibitor
Inhibition mechanism
Irinotecan-induced diarrhea
Discovery of a highly specific and efficacious inhibitor of human carboxylesterase 2 by large-scale screening
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 137, 页码: 261-269
作者:
Song, Yun-Qing
;
Guan, Xiao-Qing
;
Weng, Zi-Miao
;
Wang, Ya-Qiao
;
Chen, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/02
Glabridin
Human carboxylesterase 2 (CES2A)
Specific inhibitor
Inhibition mechanism
Irinotecan-induced diarrhea
Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2
期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 77, 页码: 320-329
作者:
Zou, Li-Wei
;
Weng, Zi-Miao
;
Ge, Guang-Bo
;
Dou, Tong-Yi
;
Wang, Ping
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/06/20
Flavonoids
Human Carboxylesterase 2 (Hce2)
Structure-inhibition Relationships
Selectivity
Inhibition Mechanism
Anticancer Drug Targets of Salvia Phytometabolites: Chemistry, Biology and Omics
期刊论文
CURRENT DRUG TARGETS, 2018, 卷号: 19, 期号: 1, 页码: 1-20
作者:
Hao, Da-Cheng
;
Ge, Guang-Bo
;
Xiao, Pei-Gen
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/06/20
Salvia
Terpene
Phenolics
Anticancer Diversity
Omics
Drug Target
Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2
期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 77
作者:
Weng, Zi-Miao
;
Ge, Guang-Bo
;
Dou, Tong-Yi
;
Wang, Ping
;
Liu, Ping-Kun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Flavonoids
Human carboxylesterase 2 (hCE2)
Structure-inhibition relationships
Selectivity
Inhibition mechanism
Bysspectin A, an unusual octaketide dimer and the precursor derivatives from the endophytic fungus Byssochlamys spectabilis IMM0002 and their biological activities
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145
作者:
Wu, Yu-Zhuo
;
Zhang, Hua-Wei
;
Sun, Zhao-Hui
;
Dai, Jun-Gui
;
Hu, You-Cai
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
Byssochlamys spectabilis
Polyketide-derived octaketide dimer
Human carboxylesterase 2
Selective inhibitor
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