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Topological control for 2D minimum compliance topology optimization using SIMP method
期刊论文
Structural and Multidisciplinary Optimization, 2022, 卷号: 65, 期号: 1, 页码: 16
作者:
Q. L. Wang
;
H. T. Han
;
C. Wang and Z. Y. Liu
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浏览/下载:0/0
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提交时间:2023/06/14
Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14
作者:
Zhang, Chun
;
Sun, Yi-Tao
;
Gao, Li-Xin
;
Feng, Bo
;
Yan, Xue
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  |  
浏览/下载:21/0
  |  
提交时间:2022/01/18
Discovery of 1,5-Dihydro-4H-imidazol-4-one Derivatives as Potent, Selective Antagonists of CXC Chemokine Receptor 2
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 5, 页码: 836-845
作者:
Che, Jinxin
;
Wang, Zhilong
;
Shen, Zheyuan
;
Zhuang, Weihao
;
Ying, Huazhou
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  |  
浏览/下载:61/0
  |  
提交时间:2021/08/17
cancer metastasis
CXCR1
CXCR2
selectivity
antagonist
1,5-dihydro-4H-imidazol-4-one
Determination of geomaterial mechanical parameters based on back analysis and reduced-order model
期刊论文
COMPUTERS AND GEOTECHNICS, 2021, 卷号: 132, 页码: 13
作者:
Zhao, Hongbo
;
Chen, Bingrui
;
Li, Shaojun
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浏览/下载:218/0
  |  
提交时间:2021/05/25
Geomechanics
Geomaterial
Back analysis
Reduced-order model
Simple homology global optimization
Exploring the autoinhibition mechanism of the C-terminal guanine nucleotide exchange factor module of Trio through molecular dynamics simulations
期刊论文
CHEMICAL PHYSICS LETTERS, 2019, 卷号: 730, 页码: 100-104
作者:
Zhang, Yuxin
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浏览/下载:52/0
  |  
提交时间:2019/12/02
TrioC
DH-PH interface
MD
Hydrogen bond
Homology Modeling-Based in Silico Affinity Maturation Improves the Affinity of a Nanobody.
期刊论文
International Journal of Molecular Sciences, 2019, 卷号: Vol.20 No.17, 页码: 4187
作者:
Cheng, Xin
;
Wang, Jiewen
;
Kang, Guangbo
;
Hu, Min
;
Yuan, Bo
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浏览/下载:11/0
  |  
提交时间:2019/11/21
homology modeling
in vitro affinity maturation
nanobody
rational design
Design of environmentally friendly neonicotinoid insecticides with bioconcentration tuning and Bi-directional selective toxic effects
期刊论文
Journal of Cleaner Production, 2019, 卷号: Vol.221, 页码: 113-121
作者:
Yuanyuan Zhao
;
Yu Li
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浏览/下载:3/0
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提交时间:2019/12/17
New pesticide
Molecule modification
Three-dimensional quantitative structure–activity relationship
Two-dimensional quantitative structure–activity relationship
Homology modeling
Molecular docking
Design of environmentally friendly neonicotinoid insecticides with bioconcentration tuning and Bi-directional selective toxic effects
期刊论文
Journal of Cleaner Production, 2019
作者:
Yuanyuan Zhao
;
Yu Li
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  |  
浏览/下载:11/0
  |  
提交时间:2019/12/17
New pesticide
Molecule modification
Three-dimensional quantitative structure–activity relationship
Two-dimensional quantitative structure–activity relationship
Homology modeling
Molecular docking
Computer-Aided Drug Design in Epigenetics
期刊论文
FRONTIERS IN CHEMISTRY, 2018, 卷号: 6
作者:
Lu, Wenchao
;
Zhang, Rukang
;
Jiang, Hao
;
Zhang, Huimin
;
Luo, Cheng
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  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
drug discovery
epigenetics
small-molecule inhibitor
computer-aided drug design
virtual screening
Molecular docking, binding free energy analysis, and biological evaluation of bisabolonalone hydrazone carboxamides as H+,K+-ATPase reversible inhibitors
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2018, 卷号: 27, 期号: 1, 页码: 332-340
作者:
She, Xin-Xin
;
Dong, Qing
;
Luo, Hua-Jun
;
Wang, Jun-Zhi
;
Huang, Nian-Yu
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  |  
浏览/下载:49/0
  |  
提交时间:2019/06/20
Molecular Docking
Binding
Free Energy
Bisabolonalone Hydrazone Carboxamides
H++
k+-atpase
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