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上海药物研究所 [8]
上海营养与健康研究所 [4]
厦门大学 [2]
山东大学 [2]
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期刊论文 [23]
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Therapeutic potential of enzymatically extracted eumelanin from squid ink in type 2 diabetes mellitus ICR mice: Multifaceted intervention against hyperglycemia, oxidative stress and depression
期刊论文
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2023, 页码: 15
作者:
Song, Wen
;
Xing, Ronge
;
Yang, Haoyue
;
Liu, Song
;
Yu, Huahua
收藏
  |  
浏览/下载:121/0
  |  
提交时间:2023/11/30
type 2 diabetes mellitus (T2DM)
eumelanin
hypoglycemic activity
antioxidant activity
antidepressant activity
Porphyra haitanensis Polysaccharides Attenuates Blood Lipid via Gut-Liver Axis in Diet-Induced High-Fat Mesocricetus auratus through Multiple Integrated Omics
期刊论文
MOLECULAR NUTRITION & FOOD RESEARCH, 2023, 页码: 15
作者:
Zeng, Hongliang
;
Chen, Peilin
;
Wang, Zhiyun
;
Hu, Xiaoke
;
Zhang, Yi
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/07/18
gut microbiota
gut-liver axis
hyperlipidemia
lipomics
Porphyra haitanensis polysaccharide
transcriptomics
AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Shui-mei
;
Xie, Zhi-fu
;
Zhang, Yang-ming
;
Zhang, Xin-wen
;
Zhou, Chen-dong
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
adenosine 5 '-monophosphate-activated protein kinase
AMPK activator
C24
liver
triglycerides
cholesterol
VLDL
hypolipidemic drug
metabolic syndrome
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
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  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2019, 期号: 10, 页码: 1396-1411
作者:
Xie, Cen
;
Takahashi, Shogo
;
Brocker, Chad N.
;
He, Shijun
;
Chen, Li
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Peroxisome proliferator-activated receptor alpha
Wy-14,643
Bile acid homeostasis
Farnesoid X receptor
Metabolomics
Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene
期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 13
作者:
Han, Yamei
;
Hu, Zhimin
;
Cui, Aoyuan
;
Liu, Zhengshuai
;
Ma, Fengguang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Caffeine programs hepatic SIRT1-related cholesterol synthesis and hypercholesterolemia via A2AR/cAMP/PKA pathway in adult male offspring rats
期刊论文
TOXICOLOGY, 2019, 卷号: 418
作者:
Hu, Shuwei
;
Lin, Kexin
;
Luo, Hanwen
;
Xu, Dan
;
Chen, Liaobin
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
Caffeine
Hepatic cholesterol synthesis
Histone acetylation
Hypercholesterolemia
A Novel Role for CRTC2 in Hepatic Cholesterol Synthesis Through SREBP-2 (vol 66, pg 481, 2017)
期刊论文
HEPATOLOGY, 2018, 卷号: 67, 期号: 3, 页码: 1188-1188
作者:
Li, Yujie
;
Song, Yongfeng
;
Zhao, Meng
;
Guo, Yanjing
;
Yu, Chunxiao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/11
Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 8, 页码: 2319-2327
作者:
Xu, Yuhui
;
Niu, Yanfen
;
Gao, Yuan
;
Wang, Fang
;
Qin, Wanying
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2017/10/23
Insulin-resistance
Tuberculata Beumee
Metabolic Syndrome
Srebp
Liver
Cholesterol
Constituents
Homeostasis
Inhibition
Receptors
Dicer1/miR-29/HMGCR axis contributes to hepatic free cholesterol accumulation in mouse nonalcoholic steatohepatitis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 5, 页码: 660-671
作者:
Liu, Ming-xia
;
Gao, Man
;
Li, Chun-zhu
;
Yu, Cun-zhi
;
Yan, Hong
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
non-alcoholic steatohepatitis
cholesterol accumulation
Dicer1
HMGCR
microRNA-29
MCD diet-treated mice
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