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上海药物研究所 [14]
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期刊论文 [29]
会议论文 [1]
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The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39
作者:
Ma, Liying
;
Bian, Xing
;
Lin, Wenchu
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/11/30
SCLC
PI3K
HDAC
CUDC-907
PARP1
Olaparib
DSB repair
Combination treatment
The design of a novel near-infrared fluorescent HDAC inhibitor and image of tumor cells
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 17, 页码: 5
作者:
Huang, Ying
;
Ru, Hong-bo
;
Bao, Bin
;
Yu, Jia-hui
;
Li, Jia
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
HDAC
Probe
NIR
Tumor imaging
Development of a Novel Histone Deacetylase-Targeted Near-Infrared Probe for Hepatocellular Carcinoma Imaging and Fluorescence Image-Guided Surgery
期刊论文
MOLECULAR IMAGING AND BIOLOGY, 2020, 卷号: 22, 期号: 3, 页码: 476-485
作者:
Tang, Chu
;
Du, Yang
;
Liang, Qian
;
Cheng, Zhen
;
Tian, Jie
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/06/22
Specific targeting probe
Histone deacetylase
Fluorescence imaging
Hepatocellular carcinoma
Fluorescence image-guided surgery
The HDAC Inhibitor Quisinostat (JNJ-26481585) Supresses Hepatocellular Carcinoma alone and Synergistically in Combination with Sorafenib by G0/G1 phase arrest and Apoptosis induction
期刊论文
2018, 卷号: 14, 期号: 13, 页码: 1845-1858
作者:
He, Bin
;
Dai, Longfei
;
Zhang, Xiaoqian
;
Chen, Diyu
;
Wu, Jingbang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
Histone deacetylases (HDACs)
Histone deacetylases inhibitors (HDACis)
Hepatocellular Carcinoma cells (HCC cells)
quisinostat (JNJ-26481585)
sorafenib
synergistic effect
Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 4, 页码: 551-560
作者:
Sun, Jing-ya
;
Wang, Ji-dong
;
Wang, Xin
;
Liu, Hong-chun
;
Zhang, Min-min
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
HDAC
chromopeptide A
FK228
human prostate cancer
cell cycle arrest
apoptosis
cancer cell migration
PC3 xenograft model
Design, synthesis and biological evaluation of thienopyrimidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 128, 页码: 293-299
作者:
Wang, Jiang
;
Su, Mingbo
;
Li, Tingting
;
Gao, Anhui
;
Yang, Wei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
HDAC inhibitor
Anti-proliferation
Western blot
Thienopyrimidine
Structure-activity relationship
HDAC inhibitor TSA ameliorates mechanical hypersensitivity and potentiates analgesic effect of morphine in a rat model of bone cancer pain by restoring μ-opioid receptor in spinal cord
期刊论文
Brain Research, 2017, 卷号: 1669, 页码: 97-105
作者:
Hou, Xinran
;
Weng, Yingqi*
;
Ouyang, Bihan
;
Ding, Zhuofeng
;
Song, Zongbin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
BCP
bone cancer pain
TSA
trichostatin A
MOR
mu-opioid receptor
HDACs
histone deacetylases
HDACi
histone deacetylase inhibitors
PWMT
paw withdrawal mechanical threshold
PWTL
paw withdrawal thermal latency
Bone cancer pain
Mechanical hypersensitivity
Mu-opioid receptor
Histone deacetylase inhibitor
Trichostatin A
Tip60: Main Functions and Its Inhibitors
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2017, 卷号: 17, 期号: 8, 页码: 675-682
作者:
Zhang, Xiaoli
;
Wu, Jiyong
;
Luan, Yepeng
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
Cancer
epsilon-amino
HATs
HDACs
histone acetyltransferase
inhibitor
Tip60
marinederivedchromopeptideaanovelclassihdacinhibitorsuppresseshumanprostatecancercellproliferationandmigration
期刊论文
actapharmacologicasinica, 2017, 卷号: 38, 期号: 4, 页码: 551
作者:
Sun Jingya
;
Wang Jidong
;
Wang Xin
;
Liu Hongchun
;
Zhang Minmin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
HISTONE DEACETYLASE INHIBITORS
ANDROGEN DEPRIVATION THERAPY
ROMIDEPSIN
VORINOSTAT
EXPRESSION
RESISTANCE
TRIAL
DEPSIPEPTIDE
MITOXANTRONE
ABIRATERONE
HDAC
chromopeptide A
FK228
human prostate cancer
cell cycle arrest
apoptosis
cancer cell migration
PC3 xenograft model
Inhibition of Histone Deacetylase 3 (HDAC3) Mediates Ischemic Preconditioning and Protects Cortical Neurons against Ischemia in Rats
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2016, 卷号: 9
作者:
Yang, Xiaoyu
;
Wu, Qimei
;
Zhang, Lei
;
Feng, Linyin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
preconditioning (PC)
HDAC3
MCAO
RGFP966
calpain
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