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Simulating androgen receptor selection in designer yeast
期刊论文
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2022, 卷号: 7
作者:
Zhang, Haoran
;
Zhang, Lu
;
Xu, Yipeng
;
Chen, Shaoyong
;
Ma, Zhenyi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/23
Androgen receptor mutations
Androgen receptor antagonists
Prostate cancer
Saccharomyces cerevisiae
Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:
Lu, Dasheng
;
Liu, Yameng
;
Luo, Yuhong
;
Zhao, Jie
;
Feng, Chao
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/01/18
Fatty acid oxidation
Acylcarnitines
FXR
FGF15/19
PGC1 alpha
Transcriptomics
Metabolomics
Differential Expression of Metabolism-Related Genes in Plateau Pika (Ochotona curzoniae) at Different Altitudes on the Qinghai-Tibet Plateau
期刊论文
FRONTIERS IN GENETICS, 2022, 卷号: 12
作者:
Zhu, HJ
;
Zhong, L
;
Li, J
;
Wang, SQ
;
Qu, JP
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/02
Evaluation of the Estrogenic/Antiestrogenic Activities of Perfluoroalkyl Substances and Their Interactions with the Human Estrogen Receptor by Combining In Vitro Assays and In Silico Modeling
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 22, 页码: 14514-14524
作者:
Li, Juan
;
Cao, Huiming
;
Feng, Hongru
;
Xue, Qiao
;
Zhang, Aiqian
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  |  
浏览/下载:24/0
  |  
提交时间:2021/09/14
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:
Bi, Xiaoyang
;
Chen, Yu
;
Sun, Zhongya
;
Lu, Wenchao
;
Xu, Pan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Drug design
CBP
Bromodomain
Inhibitor
Acute myeloid leukemia
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
Mechanistic in silico modeling of bisphenols to predict estrogen and glucocorticoid disrupting potentials
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 728, 页码: 1-11
作者:
Chen, Qinchang
;
Zhou, Chengzhuo
;
Shi, Wei
;
Wang, Xiaoxiang
;
Xia, Pu
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/09/14
Endocrine disruptor
Estrogen receptor
Glucocorticoid receptor
Coregulators
Accelerated molecular dynamics simulations
Binding free energy
TAF5L functions as transcriptional coactivator of MITF involved in the immune response of the clam Meretrix petechialis
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2020, 卷号: 98, 页码: 1017-1023
作者:
Wang, Di
;
Zhang, Shujing
;
Liu, Baozhong
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/09/23
TAF5L
MITF
Innate immunity
Meretrix petechialis
A molecular switch regulating transcriptional repression and activation of PPAR gamma
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 14
作者:
Shang, Jinsai
;
Mosure, Sarah A.
;
Zheng, Jie
;
Brust, Richard
;
Bass, Jared
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:
Zhang, Feng-cai
;
Sun, Zhong-ya
;
Liao, Li-ping
;
Zuo, Yu
;
Zhang, Dan
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
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