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Defining the minimum substrate and charge recognition model of gamma-secretase 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 10, 页码: 1412-1424
作者:  Yan, Yan;  Xu, Ting-Hai;  Melcher, Karsten;  Xu, H. Eric
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the gamma - secretase cleavage sites 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 38, 页码: 15826-15837
作者:  Yan, Yan;  Xu, Ting-Hai;  Harikumar, Kaleeckal G.;  Miller, Laurence J.;  Melcher, Karsten
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Alzheimer's disease-associated mutations increase amyloid precursor protein resistance to gamma-secretase cleavage and the A beta 42/A beta 40 ratio 期刊论文
CELL DISCOVERY, 2016, 卷号: 2
作者:  Xu, Ting-Hai;  Yan, Yan;  Kang, Yanyong;  Jiang, Yi;  Melcher, Karsten
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 卷号: 112, 期号: 11, 页码: 3344-3349
作者:  Dang, SY;  Wu, SJ;  Wang, JW;  Li, HB;  Huang, M
收藏  |  浏览/下载:18/0  |  提交时间:2015/07/22
Hydrogen peroxide promotes A beta production through JNK-dependent activation of gamma-secretase 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 卷号: 283, 期号: 25, 页码: 17721-17730
作者:  Shen, CY;  Chen, YF;  Liu, HQ;  Zhang, KJ;  Zhang, T
收藏  |  浏览/下载:15/0  |  提交时间:2015/07/22


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