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昆明植物研究所 [4]
上海药物研究所 [3]
大连化学物理研究所 [2]
物理研究所 [1]
西双版纳热带植物园 [1]
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期刊论文 [16]
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Rational design of a near-infrared fluorescence probe for highly selective sensing butyrylcholinesterase (BChE) and its bioimaging applications in living cell
期刊论文
TALANTA, 2020, 卷号: 219, 页码: 10
作者:
Ma, Jianlong
;
Lu, Xiaofeng
;
Zhai, Honglin
;
Li, Qiang
;
Qiao, Li
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/12/15
Fluorescent probe
Rational design
Highly selective
Butyrylcholinesterase
Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-A beta Aggregation Activity through Molecular Docking-Based Virtual Screening
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 2, 页码: 161-166
作者:
Liu, Guangpu
;
Jiao, Yang
;
Lin, Yongqiang
;
Hao, Haifang
;
Dou, Yanli
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/07/01
selective acetylcholinesterase inhibitor
amyloid beta aggregation
neuroprotectant
molecular docking
molecular dynamics simulation
Rational design of a near-infrared fluorescence probe for highly selective sensing butyrylcholinesterase (BChE) and its bioimaging applications in living cell
期刊论文
Talanta, 2020, 期号: 219, 页码: 121278
作者:
Jianlong Ma
;
Xiaofeng Lu
;
Honglin Zhai
;
Qiang Li
;
Li Qiao
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/11/18
Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-A beta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 21
作者:
Jiang, Cheng-Shi
;
Ge, Yong-Xi
;
Cheng, Zhi-Qiang
;
Wang, Yin-Yin
;
Tao, Hong-Rui
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
selective BChE inhibitor
virtual screening
structural optimization
molecular dynamics
anti-A beta aggregation
Pharmacophore-based drug design for the identification of novel butyrylcholinesterase inhibitors against Alzheimer's disease
期刊论文
PHYTOMEDICINE, 2019, 卷号: 54, 期号: 2, 页码: 278-290
作者:
Jiang, YY (Jiang, Yingying)[ 2 ]
;
Gao, HW (Gao, Hongwei)[ 1,2 ]
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/03/19
Alzheimer's disease (AD)
Butyrylcholinesterase (BChE)
Flavonoids
Pharmacophore models
Molecular docking
De novo evolution
Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors
期刊论文
Bioorganic chemistry, 2018, 卷号: 83, 页码: 277-288
作者:
Cheng, Zhi-Qiang
;
Zhu, Kong-Kai
;
Zhang, Juan
;
Song, Jia-Li
;
Muehlmann, Luis Alexandre
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  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Targeting neurotrophic factors and their receptors, but not cholinesterase or neurotransmitter, in the neurotoxicity of TDCPP in Chinese rare minnow adults (Gobiocypris rarus)
期刊论文
ENVIRONMENTAL POLLUTION, 2016, 卷号: 208, 期号: 0, 页码: 670-677
作者:
Zha, Jinmiao
;
Wang, Zijian
;
Li, Jiasu
;
Yuan, Lilai
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2017/04/01
Organophosphate Flame Retardants
Neurological Effects
Cholinesterase And Neurotransmitter Systems
Neurotrophic Factors
Chinese Rare Minnow
Potent AChE and BChE inhibitors isolated from seeds of Peganum harmala Linn by a bioassay-guided fractionation
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2015, 卷号: 168
作者:
Yang, Yadi
;
Cheng, Xuemei
;
Liu, Wei
;
Chou, Guixin
;
Wang, Zhengtao
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Alkaloids
Peganum harmala
Cholinesterase inhibitors
Acetylcholinesterase
Butyrylcholinesterase
Reaction pathways and free energy profiles for cholinesterase-catalyzed hydrolysis of 6-monoacetylmorphine
期刊论文
organic & biomolecular chemistry, 2014, 卷号: 12, 期号: 14, 页码: 2214-2227
作者:
Qiao, Yan
;
Han, Keli
;
Zhan, Chang-Guo
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2015/11/16
Two New Triterpenoids from Gelsemium elegans and Aglaia odorata
期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2013, 卷号: 8, 期号: 10, 页码: 1373-1376
作者:
Liu, Bing
;
Yang, Lin
;
Xu, You-Kai
;
Liao, Shang-Gao
;
Luo, Huai-Rong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2014/01/13
Gelsemium elegans
Aglaia odorata
Eleganoside A
Odoratanone A
AChE/BchE
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