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CORC

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Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199
作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying
收藏  |  浏览/下载：40/0  |  提交时间：2021/11/04
Design of G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) soft drugs with reduced gallbladder-filling effects 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 12
作者:  Han, Fanghui;  Ning, Mengmeng;  Cao, Hua;  Ye, Yangliang;  Feng, Ying
收藏  |  浏览/下载：32/0  |  提交时间：2020/12/21
The triterpenoid sapogenin (2 alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling 期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 9, 页码: 10
作者:  Xie, Zhifu;  Jiang, Haowen;  Liu, Wei;  Zhang, Xinwen;  Chen, Dakai
收藏  |  浏览/下载：32/0  |  提交时间：2020/12/21
TGR5 agonist ameliorates insulin resistance in skeletal muscles and improves glucose homeostasis in diabetic mice 期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2019, 卷号: 99, 页码: 45-56
作者:  Huang, Suling;  Ma, Shanyao;  Ning, Mengmeng;  Yang, Wenji;  Ye, Yangliang
收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01
Chronic Methylmercury Exposure Induces Production of Prostaglandins: Evidence From A Population Study and A Rat Dosing Experiment 期刊论文
Environmental Science & Technology, 2019, 卷号: 53, 期号: 13, 页码: 7782-7791
作者:  Hang-kin Kong;  Chun-fang Gan;  Min Xiong;  Kevin Wing-hin Kwok;  Gilbert Chiu-sing Lui;  Ping Li;  Hing Man Chan;  Samuel Chun-lap Lo
收藏  |  浏览/下载：16/0  |  提交时间：2020/05/07
Plasma bile acid changes in type 2 diabetes correlated with insulin secretion in two-step hyperglycemic clamp 期刊论文
JOURNAL OF DIABETES, 2018, 卷号: 10, 期号: 11, 页码: 874-885
作者:  Xie, Xiaoyan;  Ma, Jing;  Xu, Min;  Zhao, Xinjie;  Gu, Weiqiong
收藏  |  浏览/下载：63/0  |  提交时间：2019/06/20
D-chiro-inositol effectively attenuates cholestasis in bile duct ligated rats by improving bile acid secretion and attenuating oxidative stress 期刊论文
2018, 卷号: 39, 期号: 2, 页码: 213-221
作者:  Zhao, Shuang-shuang;  Li, Na-ren;  Zhao, Wu-li;  Liu, Hong;  Ge, Mao-xu
收藏  |  浏览/下载：7/0  |  提交时间：2020/01/03
Beneficial effect of resveratrol on α‑naphthyl isothiocyanate‑induced cholestasis via regulation of the FXR pathway 期刊论文
Molecular medicine reports, 2018, 卷号: 17, 期号: 1, 页码: 1863-1872
作者:  Ding, Lili;  Zhang, Binfeng;  Li, Jinmei;  Yang, Li;  Wang, Zhengtao
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1359-1369
作者:  Ma, Shan-yao;  Ning, Meng-meng;  Zou, Qing-an;  Feng, Ying;  Ye, Yang-liang
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
Intestinally-targeted TGR5 agonists equipped with quaternary ammonium have an improved hypoglycemic effect and reduced gallbladder filling effect 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:  Cao, Hua;  Chen, Zhi-Xiang;  Wang, Kai;  Ning, Meng-Meng;  Zou, Qing-An
收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08

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