×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [9]
复旦大学上海医学院 [3]
清华大学 [2]
上海生物化学与细胞生... [2]
北京大学 [1]
湖南农业大学 [1]
更多...
内容类型
期刊论文 [18]
会议论文 [1]
发表日期
2021 [1]
2020 [2]
2019 [1]
2018 [1]
2017 [3]
2016 [2]
更多...
学科主题
Biochemist... [1]
Science & ... [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共19条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 16, 页码: 6
作者:
Su, Zhicheng
;
Yang, Tingyuan
;
Wang, Jie
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/24
EGFR
NSCLC
C797S
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant
期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:
Hu, Xianglong
;
Xun, Qiuju
;
Zhang, Tao
;
Zhu, Su-Jie
;
Li, Qian
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/01
EGFR(C797S) mutant
SARs
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidine
Clinical resistance
Fourth-generation inhibitors
Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892
作者:
Liang, Xiaofei
;
Wang, Beilei
;
Chen, Cheng
;
Wang, Aoli
;
Hu, Chen
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/05/21
Comparative profiling of sarcoplasmic phosphoproteins in ovine muscle with different color stability
期刊论文
Food Chemistry, 2018, 卷号: 240, 页码: 104-111
作者:
Li, Meng
;
Li, Zheng
;
Li, Xin
;
Xin, Jianzeng
;
Wang, Ying
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/23
Meat color stability
Protein phosphorylation
Sarcoplasmic proteins
Myoglobin
Glycolytic enzyme
Evaluation of in vitro and in vivo activity of a multityrosine kinase inhibitor, AL3810, against human thyroid cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1533-1542
作者:
Xie, Qin
;
Chen, Hui
;
Ai, Jing
;
Gao, Ying-lei
;
Geng, Mei-yu
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
thyroid cancer
AL3810
multi-tyrosine kinases inhibitor
angiogenesis
RET
Synthesis and structure-activity relationship study of pyrazolo[3,4-d]pyrimidines as tyrosine kinase RET inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2544-2548
作者:
Wang, Chengyan
;
Liu, Hongchun
;
Song, Zilan
;
Ji, Yinchun
;
Xing, Li
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Tyrosine kinase RET
Pyrazolo[3,4-d]pyrimidine
Anticancer
Cell proliferation
Structure-activity relationship
evaluationofinvitroandinvivoactivityofamultityrosinekinaseinhibitoral3810againsthumanthyroidcancer
期刊论文
actapharmacologicasinica, 2017, 卷号: 38, 期号: 11, 页码: 1533
作者:
Xie Qin
;
Chen Hui
;
Al Jing
;
Gao Yinglei
;
Geng Meiyu
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
TARGETED THERAPIES
RET
CARCINOMA
MODELS
GROWTH
TUMORS
CELLS
thyroid cancer
AL3810
multi-tyrosine kinases inhibitor
angiogenesis
RET
Necrotic pyknosis is a morphologically and biochemically distinct event from apoptotic pyknosis
期刊论文
JOURNAL OF CELL SCIENCE, 2016
Hou, Lin
;
Liu, Kai
;
Li, Yuhong
;
Ma, Shuang
;
Ji, Xunming
;
Liu, Lei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/04
BAF phosphorylation
Drosophila genetics
Apoptosis
Cell death morphology
Necrosis
Pyknosis
TO-AUTOINTEGRATION FACTOR
PROGRAMMED CELL-DEATH
DNA FRAGMENTATION
NEURONAL NECROSIS
BAF
DROSOPHILA
MECHANISMS
CHROMATIN
GENE
NUCLEUS
Xijiao Dihuang Decoction combined with Yinqiao Powder reverses influenza virus-induced F-actin reorganization in PMVECs by inhibiting ERM phosphorylation
期刊论文
Journal of Traditional Chinese Medical Sciences, 2016, 卷号: 3, 期号: 1
作者:
Xuan Z., Wu Y., Zhang C., Zhang S., Chen X., Li S., Hao Y., Wang Q., Wang X., Zhang S.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/06
©版权所有 ©2017 CSpace - Powered by
CSpace