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上海药物研究所 [6]
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期刊论文 [20]
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Nucleic Acid Aptamers for Molecular Diagnostics and Therapeutics: Advances and Perspectives
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020
作者:
Li, Long
;
Xu, Shujuan
;
Yan, He
;
Li, Xiaowei
;
Yazd, Hoda Safari
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/10/26
aptamers
artificial bases
biomarker discovery
cancer classification
SELEX
Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9
作者:
Han, Jie
;
Tian, Yucheng
;
Yu, Liang
;
Zhang, Qilin
;
Xu, Xi
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  |  
浏览/下载:61/0
  |  
提交时间:2020/12/24
Ubiquitination
High throughput screening
Drug discovery
USP8
Long-term history of sediment inputs to the eastern Arabian Sea and its implications for the evolution of the Indian summer monsoon since 3.7 Ma
期刊论文
GEOLOGICAL MAGAZINE, 2020, 卷号: 157, 期号: 6, 页码: 908-919
作者:
Cai, Mingjiang
;
Xu, Zhaokai
;
Clift, Peter D.
;
Khim, Boo-Keun
;
Lim, Dhongil
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  |  
浏览/下载:27/0
  |  
提交时间:2020/09/25
Arabian Sea
clay minerals
Deccan Traps
Indian summer monsoon
Indus River
International Ocean Discovery Program
IODP Site U1456
Transfer posterior error probability estimation for peptide identification
期刊论文
BMC Bioinformatics, 2020, 卷号: 21, 期号: 1
作者:
Yi,Xinpei
;
Gong,Fuzhou
;
Fu,Yan
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  |  
浏览/下载:15/0
  |  
提交时间:2020/05/24
Proteomics
Mass spectrometry
Quality control
Posterior error probability
Local false discovery rate
Transfer learning
Geochemical Records of the Provenance and Silicate Weathering/Erosion From the Eastern Arabian Sea and Their Responses to the Indian Summer Monsoon Since the Mid-Pleistocene
期刊论文
PALEOCEANOGRAPHY AND PALEOCLIMATOLOGY, 2020, 卷号: 35, 期号: 4, 页码: 18
作者:
Chen, Hongjin
;
Xu, Zhaokai
;
Lim, Dhongil
;
Clift, Peter D.
;
Chang, Fengming
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  |  
浏览/下载:27/0
  |  
提交时间:2020/09/24
International Ocean Discovery Program
Site U1456
eastern Arabian Sea
major and trace elements
Sr-Nd isotopes
Indian summer monsoon
RNA Methylation m(6)A: A New Code and Drug Target?
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 卷号: 38, 期号: 4, 页码: 420-421
作者:
Lai, Gan-Qiang
;
Zhou, Lin-Lin
;
Yang, Cai-Guang
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  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
m(6)A
Epitranscriptomics
Small-molecule intervention
Drug discovery
RNA
Learning to Recognize Visual Concepts for Visual Question Answering With Structural Label Space
期刊论文
IEEE JOURNAL OF SELECTED TOPICS IN SIGNAL PROCESSING, 2020, 卷号: 14, 期号: 3, 页码: 494-505
作者:
Gao, Difei
;
Wang, Ruiping
;
Shan, Shiguang
;
Chen, Xilin
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  |  
浏览/下载:20/0
  |  
提交时间:2020/12/10
Visualization
Semantics
Grounding
Knowledge discovery
Sports
Task analysis
Image recognition
Visual question answering
visual concept recognition
structural label space
Recent advances in dopaminergic strategies for the treatment of Parkinson's disease
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Mao, Qi
;
Qin, Wang-zhi
;
Zhang, Ao
;
Ye, Na
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  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Parkinson's disease
dopamine
D-1 receptor
D-2 receptor
allosteric modulator
neuroprotection
multitarget
drug discovery and development
neurodegenerative diseases
Synthesis and Target Identification of Benzoxepane Derivatives as Potential Anti-Neuroinflammatory Agents for Ischemic Stroke
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 卷号: 59, 期号: 6, 页码: 2429-2439
作者:
Gao, Cheng-Long
;
Hou, Gui-Ge
;
Liu, Jin
;
Ru, Tong
;
Xu, Ya-Zhou
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
anti-inflammatory
drug discovery
heterocycles
photoaffinity labeling
proteins
Big geodata mining: Objective, connotations and research issues
期刊论文
JOURNAL OF GEOGRAPHICAL SCIENCES, 2020, 卷号: 30, 期号: 2, 页码: 251-266
作者:
Pei, Tao
;
Song, Ci
;
Guo, Sihui
;
Shu, Hua
;
Liu, Yaxi
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/05/19
big earth observation data
big human behavior data
geographical spatiotemporal pattern
spatio-temporal heterogeneity
knowledge discovery
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