CORC

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CORC

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Design, synthesis and biological evaluation of thioether-containing lenalidomide and pomalidomide derivatives with anti-multiple myeloma activity 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 13
作者:  Wang, Yuhong;  Mi, Tian;  Li, Yiming;  Kan, Weijuan;  Xu, Gaoya
收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
Determination of the antidiabetic chemical basis of Phellodendri Chinensis Cortex by integrating hepatic disposition in vivo and hepatic gluconeogenese inhibition in vitro 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 263, 页码: 10
作者:  Tian, Xiaoting;  Xu, Zhou;  Hu, Pei;  Yu, Yanyan;  Li, Zhixiong
收藏  |  浏览/下载：74/0  |  提交时间：2020/12/21
The triterpenoid sapogenin (2 alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling 期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 9, 页码: 10
作者:  Xie, Zhifu;  Jiang, Haowen;  Liu, Wei;  Zhang, Xinwen;  Chen, Dakai
收藏  |  浏览/下载：32/0  |  提交时间：2020/12/21
Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery 期刊论文
CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 8, 页码: 2260-2268
作者:  Jiang, Haowen;  Zhou, X. Edward;  Shi, Jingjing;  Zhou, Zhi;  Zhao, Guanguan
收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01
Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 22, 页码: 5780-5791
作者:  Guo, Bin;  Guo, Shimeng;  Huang, Jing;  Li, Jingya;  Li, Jia
收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08
Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:  Gu, Zhanni;  Wu, Lingyan;  Duan, Yanan;  Wang, Jiang;  Zhou, Shengbin
收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08
Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464
作者:  Zhou, Shengbin;  Duan, Yanan;  Wang, Jiang;  Zhang, Jin;  Sun, Haifeng
收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08
Synthesis of Aromatic Amide Derivatives and Their Biological Evaluation against Protein Tyrosine Phosphatase 1B and Scr Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2016, 卷号: 36, 期号: 9, 页码: 2142-2149
作者:  Wang Wenlong;  Luo Huan;  Gao Ya;  Gao Lixin;  Sheng Li
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08
Chromopeptide A, a highly cytotoxic depsipeptide from the marine sediment-derived bacterium Chromobacterium sp. HS-13-94 期刊论文
ACTA PHARMACEUTICA SINICA B, 2015, 卷号: 5, 期号: 1, 页码: 62-66
作者:  Zhou, Zhenfang;  Wang, Xin;  Zhang, Hui;  Sun, Jingya;  Zheng, Linghui
收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08
chromopeptideaahighlycytotoxicdepsipeptidefromthemarinesedimentderivedbacteriumchromobacteriumsphs1394 期刊论文
actapharmaceuticasinicab, 2015, 卷号: 5, 期号: 1, 页码: 62
作者:  Zhou Zhenfang;  Wang Xin;  Zhang Hui;  Sun Jingya;  Zheng Linghui
收藏  |  浏览/下载：3/0  |  提交时间：2020/07/01

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