CORC

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CORC

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SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming
收藏  |  浏览/下载：37/0  |  提交时间：2021/05/24
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:  Zhang, Ning;  Tian, Yu-Nan;  Zhou, Li-Na;  Li, Meng-Zhu;  Chen, Hua-Dong
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:  Liu, Yu-ting;  Ding, Hui-hua;  Lin, Ze-min;  Wang, Que;  Chen, Li
收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24
Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文
Cell Death & Disease, 2021, 卷号: 12, 期号: 2, 页码: 1
作者:  Ning Zhang;  Yu-Nan Tian;  Li-Na Zhou;  Meng-Zhu Li;  Hua-Dong Chen
收藏  |  浏览/下载：18/0  |  提交时间：2021/12/01
Synchrotron Radiation-Based Three-Dimensional Visualization of Angioarchitectural Remodeling in Hippocampus of Epileptic Rats 期刊论文
NEUROSCIENCE BULLETIN, 2020, 卷号: 36, 期号: 4, 页码: 333-345
作者:  Gu, Pan;  Xu, Zi-Hao;  Cao, Yu-Ze;  Liao, Sheng-Hui;  Deng, Qian-Fang
收藏  |  浏览/下载：44/0  |  提交时间：2020/07/01
Polymerase independent repression of FoxO1 transcription by sequence-specific PARP1 binding to FoxO1 promoter 期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 1, 页码: 12
作者:  Tian, Yu-Nan;  Chen, Hua-Dong;  Tian, Chang-Qing;  Wang, Ying-Qing;  Miao, Ze-Hong
收藏  |  浏览/下载：10/0  |  提交时间：2020/12/24
Structure-Based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 18, 页码: 8642-8663
作者:  Hu, Jianping;  Tian, Chang-Qing;  Damaneh, Mohammadali Soleimani;  Li, Yanlian;  Cao, Danyan
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity 期刊论文
CANCER RESEARCH, 2019, 卷号: 79, 期号: 13, 页码: 2
作者:  Chen, Hua-Dong;  Chen, Chuan-Huizi;  Wang, Yu-Ting;  Guo, Ne;  Tian, Yu-Nan
收藏  |  浏览/下载：3/0  |  提交时间：2020/07/01
Acquired resistance of phosphatase and tensin homolog-deficient cells to poly(ADP-ribose) polymerase inhibitor and Ara-C mediated by 53BP1 loss and SAMHD1 overexpression 期刊论文
CANCER SCIENCE, 2018, 卷号: 109, 期号: 3, 页码: 821-831
作者:  Wang, Yu-Ting;  Yuan, Bo;  Chen, Hua-Dong;  Xu, Lin;  Tian, Yu-Nan
收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08
Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials 期刊论文
CANCER LETTERS, 2017, 卷号: 386, 页码: 47-56
作者:  Yuan, Bo;  Ye, Na;  Song, Shan-Shan;  Wang, Yu-Ting;  Song, Zilan
收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08

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