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科研机构
上海药物研究所 [42]
内容类型
期刊论文 [42]
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2021 [6]
2020 [1]
2019 [3]
2018 [9]
2017 [6]
2016 [1]
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Synthesis and pharmacological evaluation of choroquine derivatives bearing long aminated side chains as antivirus and anti-inflammatory agents
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 8
作者:
Song, Zilan
;
Liu, Yuting
;
Xie, Chenghu
;
Tong, Xiankun
;
Wang, Xue
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/11/04
Choroquine
Aminochloroquine
Antivirus
Anti-inflammatory
Cytokines
Gut Microbiota in Adipose Tissue Dysfunction Induced Cardiovascular Disease: Role as a Metabolic Organ
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2021, 卷号: 12, 页码: 14
作者:
Yang, Xinyu
;
Zhang, Xianfeng
;
Yang, Wei
;
Yu, Hang
;
He, Qianyan
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
gut microbiota
adipose tissue dysfunction
molecular endocrinology
cardiovascular disease(s)
gut dysbiosis
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:
Zhang, Ning
;
Tian, Yu-Nan
;
Zhou, Li-Na
;
Li, Meng-Zhu
;
Chen, Hua-Dong
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Li, Yalei
;
Wang, Juan
;
Ding, Huaqian
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/05/24
Medulloblastoma
Hedgehog signaling
pathway
Drug resistance
GLI
BRD4
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yu-ting
;
Ding, Hui-hua
;
Lin, Ze-min
;
Wang, Que
;
Chen, Li
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
rheumatoid arthritis
BTK inhibitors
B cells
macrophages
RANKL
osteoclastogenesis
Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
Cell Death & Disease, 2021, 卷号: 12, 期号: 2, 页码: 1
作者:
Ning Zhang
;
Yu-Nan Tian
;
Li-Na Zhou
;
Meng-Zhu Li
;
Hua-Dong Chen
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/12/01
Manipulating the Click Reactivity of Dibenzoazacyclooctynes: From Azide Click Component to Caged Acylation Reagent by Silver Catalysis
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 6
作者:
Shi, Wei
;
Tang, Feng
;
Ao, Jiwei
;
Yu, Qun
;
Liu, Junjie
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/21
acylation
click chemistry
peptides
rearrangements
silver
Imaging Tumorous Methylglyoxal by an Activatable Near-Infrared Fluorescent Probe for Monitoring Glyoxalase 1 Activity
期刊论文
ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 期号: 24, 页码: 15577-15584
作者:
Ding, Chunyong
;
Wang, Fengyang
;
Dang, Yijing
;
Xu, Zhiai
;
Li, Lingling
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Synthesis of Arylstannanes via Palladium-Catalyzed Decarbonylative Coupling of Aroyl Fluorides
期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2019, 页码: 7
作者:
Kayumov, Muzaffar
;
Zhao, Jian-Nan
;
Mirzaakhmedov, Sharafitdin
;
Wang, Dong-Yu
;
Zhang, Ao
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
stannylation
Pd-catalyzed
acyl fluorides
decarbonylation
late-stage diversification
Transition-Metal-Free Aryl-Heteroatom Bond Formation via C-S Bond Cleavage
期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 18, 页码: 7303-7306
作者:
Zhao, Jian-Nan
;
Kayumov, Muzaffar
;
Wang, Dong-Yu
;
Zhang, Ao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
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