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科研机构
上海药物研究所 [13]
内容类型
期刊论文 [13]
发表日期
2021 [13]
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共13条,第1-10条
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发表日期:2021
专题:上海药物研究所
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A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11
作者:
Cheng, Zhiyang
;
Huang, Ying
;
Shen, Qianqian
;
Zhao, Yangrong
;
Wang, Lei
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
Cancer
beta-glucuronidase
Bioconjugation
Albumin
Camptothecin
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306
作者:
Huang, Ying
;
Wang, Lei
;
Cheng, Zhiyang
;
Yang, Biyu
;
Yu, Jiahui
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/12/01
Antitumour
Chemotherapy
SN38
Drug delivery systems
Albumin
A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage
期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 120, 页码: 12
作者:
Huang, Suling
;
Wu, Yanwei
;
Zhao, Zhuohui
;
Wu, Bing
;
Sun, Kai
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2021/08/17
Macrophage
NLRP3 inflammasome
Hepatic lipid accumulation
NASH
FXR
Structurally diverse polyprenylated acylphloroglucinols from Hypericum uralum Buch.-Ham. ex D. Don
期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 187, 页码: 7
作者:
Fang, Qiang-Qiang
;
Feng, Tong-Tong
;
Wang, Ai-Zhu
;
He, Wan-Ying
;
Wei, Ren-Jie
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/08/17
PPAPs
Hypericum uralum
Clusiaceae
Antioxidant
Cytotoxicity
Amygdala dynorphin/kappa opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zan, Gui-ying
;
Sun, Xiang
;
Wang, Yu-jun
;
Liu, Rui
;
Wang, Chen-yao
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/08/17
depression
social defeat stress
amygdala
κ
opioid receptor
dynorphin
c-fos
ERK
norBNI
Alteration of twinfilin1 expression underlies opioid withdrawal-induced remodeling of actin cytoskeleton at synapses and formation of aversive memory
期刊论文
MOLECULAR PSYCHIATRY, 2021, 页码: 19
作者:
Wang, Yu-Jun
;
Yu, Chuan
;
Wu, Wei-Wei
;
Ju, Yun-Yue
;
Liu, Yao
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/06/11
Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18
作者:
Lan, Xiao-fang
;
Olaleye, Olajide E.
;
Lu, Jun-lan
;
Yang, Wei
;
Du, Fei-fei
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2021/06/11
LianhuaQingwen
glycyrrhetic acid
24-hydroxyglycyrrhetic acid
Gancao-induced pseudoaldosteronism
licorice-induced pseudoaldosteronism
11β
-hydroxysteroid dehydrogenase 2
COVID-19
colonic microbiota
Simple and robust differentiation of Ganoderma species by high performance thin-layer chromatography coupled with single quadrupole mass spectrometry QDa
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2021, 卷号: 19, 期号: 4, 页码: 295-304
作者:
Yao Shuai
;
Zhang Jian-Qing
;
Hou Jin-Jun
;
Hu Xiao-Su
;
Wang Ling
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/06/11
High performance thin-layer chromatography
Mass spectrometry QDa
Ganoderma
Authentication
Simple and robust differentiation of Ganoderma species by high performance thin-layer chromatography coupled with single quadrupole mass spectrometry QDa
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2021, 卷号: 19, 期号: 4, 页码: 295-304
作者:
Yao Shuai
;
Zhang Jian-Qing
;
Hou Jin-Jun
;
Hu Xiao-Su
;
Wang Ling
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/06/11
High performance thin-layer chromatography
Mass spectrometry QDa
Ganoderma
Authentication
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