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浏览/检索结果: 共9条，第1-9条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Zhang, Qing;  Chen, Lin-hai;  Yang, Hui;  Fang, You-chen;  Wang, Si-wei 收藏  |  浏览/下载：45/0  |  提交时间：2022/01/18 GPR84  medium chain fatty acid receptor  GPCR  inflammatory bowel diseases  ulcerative colitis  NLRP3 inflammasome  macrophages   Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Wang, Lin;  Wu, Yan;  Yao, Sheng;  Ge, Huan;  Zhu, Ya 收藏  |  浏览/下载：86/0  |  提交时间：2021/11/04 SARS-CoV-2  natural products  virtual screening  spike protein  protein-protein interaction modulators   Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11 作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu 收藏  |  浏览/下载：45/0  |  提交时间：2021/08/17 Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 17 作者:  Lin, Lin;  Lin, Guangyao;  Zhou, Qingtong;  Bathgate, Ross A. D.;  Gong, Grace Qun 收藏  |  浏览/下载：31/0  |  提交时间：2021/08/17 Synthesis  Structure-activity relationship  Relaxin family peptide receptor 4  Selective agonist  Molecular docking   Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18 作者:  Lan, Xiao-fang;  Olaleye, Olajide E.;  Lu, Jun-lan;  Yang, Wei;  Du, Fei-fei 收藏  |  浏览/下载：75/0  |  提交时间：2021/06/11 LianhuaQingwen  glycyrrhetic acid  24-hydroxyglycyrrhetic acid  Gancao-induced pseudoaldosteronism  licorice-induced pseudoaldosteronism  11β  -hydroxysteroid dehydrogenase 2  COVID-19  colonic microbiota   W2476 represses TXNIP transcription via dephosphorylation of FOXO1 at Ser319 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 11 作者:  Zhong, Li;  Liu, Qing;  Liu, Qiaofeng;  Zhang, Shikai;  Cao, Yongbing 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 chromatin immunoprecipitation  diabetes  transcription  TXNIP  W2476   Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells 期刊论文 CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13 作者:  Wang, Yu-xiang;  Zhang, Xu;  Ma, Qing-yang;  Hu, Lan-dian;  Zhang, Xi 收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24 G protein-coupled receptors: structure- and function-based drug discovery 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 27 作者:  Yang, Dehua;  Zhou, Qingtong;  Labroska, Viktorija;  Qin, Shanshan;  Darbalaei, Sanaz 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 PI3K alpha inhibitor CYH33 triggers antitumor immunity in murine breast cancer by activating CD8(+)T cells and promoting fatty acid metabolism 期刊论文 JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9, 期号: 8, 页码: 16 作者:  Sun, Pu;  Zhang, Xi;  Wang, Rong-Jing;  Ma, Qing-Yang;  Xu, Lan 收藏  |  浏览/下载：42/0  |  提交时间：2021/11/04 tumor microenvironment  immunomodulation  immunologic memory  lymphocytes  tumor-infiltrating  macrophages