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浏览/检索结果: 共15条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Facile and Cost-Effective Route for the Synthesis of Simmerafil 期刊论文 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2432-2437 作者:  Odilov, Abdullajon;  Liu, Yin;  Hu, Tianwen;  Jiang, Xiangrui;  Suo, Jin 收藏  |  浏览/下载：20/0  |  提交时间：2022/01/18 simmerafil  PDE5 inhibitor  salicylamide  synthesis   Optimization and Development of a Scalable Palladium-Catalyzed C-H Activation Process for the Geometry-Selective Preparation of Kilograms of YLF466D, a Potent AMP-Activated Protein Kinase Activator 期刊论文 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 10, 页码: 2260-2269 作者:  Yin, Jianpeng;  Zhan, Desheng;  Ma, Hui;  Liu, Huanan;  Yu, Lifang 收藏  |  浏览/下载：36/0  |  提交时间：2021/12/16 YLF466D  AMPK activator  glucose metabolism  lipid metabolism  MIRI  domino reaction  C-H activation   Structures of full-length glycoprotein hormone receptor signalling complexes 期刊论文 NATURE, 2021, 页码: 24 作者:  Duan, Jia;  Xu, Peiyu;  Cheng, Xi;  Mao, Chunyou;  Croll, Tristan 收藏  |  浏览/下载：53/0  |  提交时间：2021/11/04 Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199 作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan 收藏  |  浏览/下载：43/0  |  提交时间：2021/11/04 PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation 期刊论文 CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 7, 页码: 10 作者:  Yang, Jun;  Wang, Juan;  Liu, Yuan;  Zhang, Yu;  Huang, Wenjing 收藏  |  浏览/下载：43/0  |  提交时间：2021/08/17 The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability 期刊论文 MOLECULAR CELL, 2021, 卷号: 81, 期号: 13, 页码: 2736-+ 作者:  Pan, Qiang;  Zhong, Shanshan;  Wang, Hanling;  Wang, Xuege;  Li, Ni 收藏  |  浏览/下载：74/0  |  提交时间：2021/11/04 Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance 期刊论文 CELL METABOLISM, 2021, 卷号: 33, 期号: 6, 页码: 1221-+ 作者:  Liu, Yi;  Liang, Guanghao;  Xu, Hongjiao;  Dong, Wenxin;  Dong, Ze 收藏  |  浏览/下载：45/0  |  提交时间：2021/08/17 Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Liu, Yi-fei;  Zhang, Lei;  Wu, Qi;  Feng, Lin-yin 收藏  |  浏览/下载：69/0  |  提交时间：2021/06/11 ischemic brain injury  paeoniflorin  MCAO  HDAC4  cytochrome c  apoptosis   Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Liu, Yi-fei;  Zhang, Lei;  Wu, Qi;  Feng, Lin-yin 收藏  |  浏览/下载：58/0  |  提交时间：2021/06/11 ischemic brain injury  paeoniflorin  MCAO  HDAC4  cytochrome c  apoptosis   Identification of the absorbed ingredients and metabolites in rats after an intravenous administration of Tanreqing injection using high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry 期刊论文 JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 16 作者:  Xie, Like;  Wang, Yangyang;  Yin, Hao;  Li, Jiajia;  Xu, Zhou 收藏  |  浏览/下载：66/0  |  提交时间：2021/05/24 COVID‐  19  metabolic profiles  quadrupole time‐  of‐  flight mass spectrometry  Tanreqing injection  traditional Chinese medicine