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浏览/检索结果: 共21条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Two New Cytotoxic Maytansinoids Targeting Tubulin from Trewia nudiflora 期刊论文 PLANTA MEDICA, 2021, 页码: 7 作者:  Lei, Chun;  Li, Ya-Nan;  Li, Jia-Nan;  Zhou, Yu-Bo;  Cui, Ming-Jun 收藏  |  浏览/下载：21/0  |  提交时间：2021/12/16 Trewia nudiflora  Euphorbiaceae  maytansinoids  cytotoxicity  tubulin polymerization   Drug target inference by mining transcriptional data using a novel graph convolutional network framework 期刊论文 PROTEIN & CELL, 2021, 页码: 21 作者:  Zhong, Feisheng;  Wu, Xiaolong 收藏  |  浏览/下载：22/0  |  提交时间：2021/12/01 drug target inference  transcriptomics  deep learning  experimental verification   5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19 作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing 收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04 NSD2  Methyltransferase  HTS  Multiple myeloma  5-Aminonaphthalene derivatives  Inhibitor   Neurovascular protection of salvianolic acid B and ginsenoside Rg1 combination against acute ischemic stroke in rats 期刊论文 NEUROREPORT, 2021, 卷号: 32, 期号: 13, 页码: 1140-1146 作者:  Fu, Yao;  Xing, Rongrong;  Wang, Linlin;  Yang, Li;  Jiang, Baohong 收藏  |  浏览/下载：25/0  |  提交时间：2021/11/04 acute ischemic stroke  ginsenoside Rg1  salvianolic acid B   Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433 作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui 收藏  |  浏览/下载：88/0  |  提交时间：2021/11/04 Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Huang, He-ming;  Fan, Shi-jie;  Zhou, Xiao-ru;  Liu, Yan-jun;  Li, Xiao 收藏  |  浏览/下载：58/0  |  提交时间：2021/11/04 nonalcoholic steatohepatitis  inflammation  histone deacetylase inhibitor  givinostat  epigenetics   Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483 作者:  Huang, Huoming;  Li, Xueping;  Xie, Peng;  Li, Xinwei;  Xu, XueJun 收藏  |  浏览/下载：29/0  |  提交时间：2021/08/17 Acylphloroglucinol derivatives with ATP citrate lyase inhibitory activities from Syzygium oblatum Wall 期刊论文 PHYTOCHEMISTRY, 2021, 卷号: 187, 页码: 7 作者:  Huang, Jin-Chang;  Liu, Yi-Nan;  Tao, Yun-Hua;  Chen, Bai-Yu;  Lei, Chun 收藏  |  浏览/下载：22/0  |  提交时间：2021/08/17 Syzygium oblatum Wall  Myrtaceae  Acylphloroglucinols  Oblatones A-I  ATP citrate lyase   Further new nardosinane-type sesquiterpenoids from the Xisha soft coral Litophyton nigrum 期刊论文 FITOTERAPIA, 2021, 卷号: 151, 页码: 4 作者:  Yang, Fan;  Hua, Qiang;  Yao, Li-Gong;  Liang, Lin-Fu;  Lu, Yan-Hua 收藏  |  浏览/下载：18/0  |  提交时间：2021/08/17 Soft coral  Litophyton nigrum  Nardosinane   Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7 作者:  Pan, Lu-lu;  Chen, Tao;  Hui, Min;  Wang, Shuo;  Fu, Li 收藏  |  浏览/下载：131/0  |  提交时间：2021/05/24 LC-MS/MS  Forsythin  Aglycone glucuronide  Aglycone sulfate  Pharmacokinetics