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浏览/检索结果: 共17条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 DCZ3301, an aryl-guanidino agent, inhibits ocular neovascularization via PI3K/AKT and ERK1/2 signaling pathways 期刊论文 EXPERIMENTAL EYE RESEARCH, 2020, 卷号: 201, 页码: 8 作者:  Xu, Kai;  Li, Bo;  Zhang, Shujie;  Hu, Fangyuan;  Xu, Zhijian 收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24 DCZ3301  Apoptosis  PI3K/AKT pathway  ERK1/2 pathway  Choroid microvascular sprouting  Corneal neovascularization   Cinnamtannin D1 Protects Pancreatic beta-Cells from Glucolipotoxicity-Induced Apoptosis by Enhancement of Autophagy In Vitro and In Vivo 期刊论文 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, 卷号: 68, 期号: 45, 页码: 12617-12630 作者:  Wang, Xin-Yi;  Zhu, Bo-Rong;  Jia, Qi;  Li, Yi-Ming;  Wang, Ting 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 cinnamtannin D1  pancreatic beta-cells  autophagy  apoptosis  type 2 diabetes   Identification of SARS-CoV-2 entry inhibitors among already approved drugs 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7 作者:  Yang, Li;  Pei, Rong-juan;  Li, Heng;  Ma, Xin-na;  Zhou, Yu 收藏  |  浏览/下载：42/0  |  提交时间：2020/12/24 COVID-19  SARS-CoV-2  virus entry inhibitors  high throughput screening assay  approved drug library  histamine receptor antagonists  clemastine   Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13 作者:  Wang, Zheng;  Li, Zeng-xia;  Zhao, Wen-cao;  Huang, Hong-bo;  Wang, Jia-qi 收藏  |  浏览/下载：82/0  |  提交时间：2020/12/24 grincamycin B  marine natural product  isocitrate dehydrogenase 1  apoptosis  ER stress  intracellular ROS  Zebrafish embryos  hematological malignancies   A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe 期刊论文 Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1 作者:  Hu,Liangning;  Li,Bo;  Chen,Gege;  Song,Dongliang;  Xu,Zhijian 收藏  |  浏览/下载：94/0  |  提交时间：2020/07/01 Multiple myeloma  Drug-resistance  DNA damage response  Cell cycle   Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5 作者:  Satheeshkumar, Rajendran;  Zhu, Rui;  Feng, Bo;  Huang, Chao;  Gao, Ya 收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 Heterocyclic bis-aryl amides  PTP1B  SHP2  Inhibitors  Structure-activity relationships (SAR)   A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib 期刊论文 CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55 作者:  Chen, Gege;  Hu, Ke;  Sun, Haiguo;  Zhou, Jinfeng;  Song, Dongliang 收藏  |  浏览/下载：97/0  |  提交时间：2020/07/01 Multiple myeloma  Bone marrow microenvironment  DNA damage  JAK2/STAT3 pathway   Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion 期刊论文 ADVANCED SCIENCE, 2020, 页码: 13 作者:  Sun, Zhongya;  Zhang, Hao;  Zhang, Yuanyuan;  Liao, Liping;  Zhou, Wen 收藏  |  浏览/下载：107/0  |  提交时间：2020/07/01 anti-metastasis activities  crystal structures  inhibitors  novel pockets  rho family proteins   Hyperprins A and B, Two Complex Meroterpenoids from Hypericum przewalskii 期刊论文 ORGANIC LETTERS, 2020, 卷号: 22, 期号: 7, 页码: 2797-2800 作者:  Zong, Jian-Fa;  Hu, Zhu;  Shao, Ying-Ying;  Shi, Qing;  Zhang, Meng-Meng 收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 11 作者:  Lu, Kang;  Li, Bo;  Zhang, Hui;  Xu, Zhijian;  Song, Dongliang 收藏  |  浏览/下载：57/0  |  提交时间：2020/07/01