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科研机构
上海药物研究所 [25]
内容类型
期刊论文 [25]
发表日期
2020 [25]
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发表日期:2020
专题:上海药物研究所
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DCZ3301, an aryl-guanidino agent, inhibits ocular neovascularization via PI3K/AKT and ERK1/2 signaling pathways
期刊论文
EXPERIMENTAL EYE RESEARCH, 2020, 卷号: 201, 页码: 8
作者:
Xu, Kai
;
Li, Bo
;
Zhang, Shujie
;
Hu, Fangyuan
;
Xu, Zhijian
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
DCZ3301
Apoptosis
PI3K/AKT pathway
ERK1/2 pathway
Choroid microvascular sprouting
Corneal neovascularization
Identification of SARS-CoV-2 entry inhibitors among already approved drugs
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:
Yang, Li
;
Pei, Rong-juan
;
Li, Heng
;
Ma, Xin-na
;
Zhou, Yu
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/12/24
COVID-19
SARS-CoV-2
virus entry inhibitors
high throughput screening assay
approved drug library
histamine receptor antagonists
clemastine
Pyrazolone derivative C29 protects against HFD-induced obesity in mice via activation of AMPK in adipose tissue
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Li, Bo-han
;
Zhang, Mei
;
Duan, Ya-nan
;
Shuai, Lin
;
Jiang, Hao-wen
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/12/21
AMP-activated protein kinase
pyrazolone derivative C29
obesity
energy expenditure
thermogenesis
inguinal white adipose tissue
white adipose browning
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
Integrative Proteomic Characterization of Human Lung Adenocarcinoma
期刊论文
CELL, 2020, 卷号: 182, 期号: 1, 页码: 245-+
作者:
Xu, Jun-Yu
;
Zhang, Chunchao
;
Wang, Xiang
;
Zhai, Linhui
;
Ma, Yiming
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/12/24
Effect of phosphatidylcholine on the stability and lipolysis of nanoemulsion drug delivery systems
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, 卷号: 583, 页码: 9
作者:
Zhang, Bo
;
Zhou, Xin
;
Miao, Yunqiu
;
Wang, Xiaoli
;
Yang, Yuting
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/12/24
Phosphatidylcholine
Nanoemulsion
Stability
Lipolysis kinetics
Curcumin
A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe
期刊论文
Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1
作者:
Hu,Liangning
;
Li,Bo
;
Chen,Gege
;
Song,Dongliang
;
Xu,Zhijian
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2020/07/01
Multiple myeloma
Drug-resistance
DNA damage response
Cell cycle
Three new bisflavonols from the seeds of Hovenia dulcis Thunb. and their anti-RSV activities
期刊论文
FITOTERAPIA, 2020, 卷号: 143, 页码: 6
作者:
Xu, Fangfang
;
Gao, Meihua
;
Li, Hua
;
Han, Xiaodong
;
Zhang, Xiaoqi
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Hovenia dulcis Thunb.
Bisflavonol
Flavonoids
Anti-RSV activity
A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib
期刊论文
CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55
作者:
Chen, Gege
;
Hu, Ke
;
Sun, Haiguo
;
Zhou, Jinfeng
;
Song, Dongliang
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2020/07/01
Multiple myeloma
Bone marrow microenvironment
DNA damage
JAK2/STAT3 pathway
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