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浏览/检索结果: 共11条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor 期刊论文 CELL RESEARCH, 2020, 页码: 11 作者:  Sun, Wen;  Chen, Li-Nan;  Zhou, Qingtong;  Zhao, Li-Hua;  Yang, Dehua 收藏  |  浏览/下载：84/0  |  提交时间：2020/12/24 Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan;  Jiang, Zheng-yuan 收藏  |  浏览/下载：85/0  |  提交时间：2020/12/24 RORγ  t  cocrystal structures  MD simulation  “  short”  inverse agonists  agonists  “  long”  inverse agonists   Structural basis for activation of the growth hormone-releasing hormone receptor 期刊论文 NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10 作者:  Zhou, Fulai;  Zhang, Huibing;  Cong, Zhaotong;  Zhao, Li-Hua;  Zhou, Qingtong 收藏  |  浏览/下载：23/0  |  提交时间：2020/12/21 AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8 作者:  Sun, Shui-mei;  Xie, Zhi-fu;  Zhang, Yang-ming;  Zhang, Xin-wen;  Zhou, Chen-dong 收藏  |  浏览/下载：25/0  |  提交时间：2020/12/24 adenosine 5 '-monophosphate-activated protein kinase  AMPK activator  C24  liver  triglycerides  cholesterol  VLDL  hypolipidemic drug  metabolic syndrome   Structural basis of GPBAR activation and bile acid recognition 期刊论文 NATURE, 2020, 页码: 29 作者:  Yang, Fan;  Mao, Chunyou;  Guo, Lulu;  Lin, Jingyu;  Ming, Qianqian 收藏  |  浏览/下载：45/0  |  提交时间：2020/12/24 Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27 作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X. 收藏  |  浏览/下载：102/0  |  提交时间：2020/07/01 embryonic ectoderm development  Enhancer of zeste homolog 2  fluorescence polarization  high-throughput screening  homogenous time-resolved fluorescence  inhibitor  polycomb repressive complex 2   Discovery of a Potent and Selective NF-kappa B-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4388-4407 作者:  Li, Zhiqiang;  Li, Xinzhi;  Su, Ming-Bo;  Gao, Li-Xin;  Zhou, Yu-Bo 收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498 作者:  Xu, Ming-ming;  Ryan, Philip;  Rudrawar, Santosh;  Quinn, Ronald J.;  Zhang, Hai-yan 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 Parkinson's disease  alpha-synuclein  imaging probes  aggregation inhibitors  thioflavin-T  mass spectrometry   Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening toward a G Protein-Coupled Receptor (vol 91, pg 8162, 2019) 期刊论文 ANALYTICAL CHEMISTRY, 2020, 卷号: 92, 期号: 6, 页码: 4689-4689 作者:  Lu, Yan;  Qin, Shanshan;  Zhang, Bingjie;  Dai, Antao;  Cai, Xiaoqing 收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition (vol 0, pg 1, 2019) 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 2 作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-feng;  Sun, Yi-ming;  Ding, Jian 收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01