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浏览/检索结果: 共16条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells 期刊论文 CELL REPORTS, 2020, 卷号: 33, 期号: 10, 页码: 24 作者:  Feng, Sisi;  Wu, Jiaying;  Qiu, Wei-Lin;  Yang, Li;  Deng, Xiaogang 收藏  |  浏览/下载：40/0  |  提交时间：2021/05/24 Synthesis of Axially Chiral Olefin-Oxazoline Ligands via Pd-Catalyzed Multiple C-H Functionalization 期刊论文 ORGANIC LETTERS, 2020, 卷号: 22, 期号: 23, 页码: 9169-9173 作者:  Li, Ling-Jun;  Chen, Jun-Jie;  Feng, Chen-Fei;  Li, Han-Yuan;  Wang, Xing 收藏  |  浏览/下载：7/0  |  提交时间：2021/05/24 Chemical constituents from the South China sea soft coral Sinularia humilis 期刊论文 NATURAL PRODUCT RESEARCH, 2020, 页码: 7 作者:  Li, Jie;  Huan, Xia-Juan;  Wu, Meng-Jun;  Chen, Zi-Hui;  Chen, Bao 收藏  |  浏览/下载：7/0  |  提交时间：2021/05/24 Soft coral  Sinularia humilis  diterpenoids  capnosane   Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan;  Jiang, Zheng-yuan 收藏  |  浏览/下载：85/0  |  提交时间：2020/12/24 RORγ  t  cocrystal structures  MD simulation  “  short”  inverse agonists  agonists  “  long”  inverse agonists   Rational Design and Evaluation of 6-(Pyrimidin-2-ylamino)-3,4-dihydroquinoxalin-2(1H)-ones as Polypharmacological Inhibitors of BET and Kinases 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 17, 页码: 9787-9802 作者:  Lv, Kaikai;  Chen, Weicong;  Chen, Danqi;  Mou, Jie;  Zhang, Huijie 收藏  |  浏览/下载：12/0  |  提交时间：2020/12/21 Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 16, 页码: 6 作者:  Su, Zhicheng;  Yang, Tingyuan;  Wang, Jie;  Lai, Mengzhen;  Tong, Linjiang 收藏  |  浏览/下载：27/0  |  提交时间：2020/12/24 EGFR  NSCLC  C797S   Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9 作者:  Han, Jie;  Tian, Yucheng;  Yu, Liang;  Zhang, Qilin;  Xu, Xi 收藏  |  浏览/下载：63/0  |  提交时间：2020/12/24 Ubiquitination  High throughput screening  Drug discovery  USP8   Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion 期刊论文 CANCER CELL, 2020, 卷号: 38, 期号: 1, 页码: 79-+ 作者:  Su, Rui;  Dong, Lei;  Li, Yangchan;  Gao, Min;  Han, Li 收藏  |  浏览/下载：33/0  |  提交时间：2020/12/24 Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma 期刊论文 JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908 作者:  Dong, Liang-qing;  Peng, Li-hua;  Ma, Li-jie;  Liu, Dong-bing;  Zhang, Shu 收藏  |  浏览/下载：64/0  |  提交时间：2020/07/01 Hepatocellular carcinoma  Tumor heterogeneity  Tumor microenvironment  Immunoediting  Neoantigen   TREK Channel Family Activator with a Well-Defined Structure-Activation Relationship for Pain and Neurogenic Inflammation 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 7, 页码: 3665-3677 作者:  Qiu, Yunguang;  Huang, Lu;  Fu, Jie;  Han, Chenxia;  Fang, Jing 收藏  |  浏览/下载：45/0  |  提交时间：2020/07/01