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浏览/检索结果: 共9条，第1-9条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15153-15186 作者:  Zheng, Wei;  Wang, Zhen;  Jiang, Xiangrui;  Zhao, Qingjie;  Shen, Jingshan 收藏  |  浏览/下载：26/0  |  提交时间：2021/05/24 Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 191, 页码: 8 作者:  Zhang, Mengqi;  Liu, Haiming;  He, Jiajin;  Gui, Yuzhou;  Qian, Hongjie 收藏  |  浏览/下载：29/0  |  提交时间：2020/12/24 TPN171  LC-MS/MS  Human plasma  Protein precipitation   Automated design and optimization of multitarget schizophrenia drug candidates by deep learning 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16 作者:  Tan, Xiaoqin;  Jiang, Xiangrui;  He, Yang;  Zhong, Feisheng;  Li, Xutong 收藏  |  浏览/下载：37/0  |  提交时间：2020/12/21 Schizophrenia  Multitarget antipsychotic drugs  Recurrent neural network  Multitask deep neural network  Automated drug design   Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-Dependent TFEB Signaling Pathway 期刊论文 CIRCULATION RESEARCH, 2020, 卷号: 127, 期号: 4, 页码: 534-549 作者:  You, Yan;  Bao, Wei-Lian;  Zhang, Su-Lin;  Li, Hai-Dong;  Li, Hui 收藏  |  浏览/下载：48/0  |  提交时间：2020/12/24 atherosclerosis  foam cell  lipid metabolism  monocytes  sorting nexin   Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Tian, Qian-qian;  Zhu, Yun-ting;  Diao, Xing-xing;  Zhang, Xiang-lei;  Xu, Ye-chun 收藏  |  浏览/下载：69/0  |  提交时间：2020/12/24 PDE5 inhibitor  TPN729  M3  species difference  pharmacokinetics  metabolite identification   Downregulation of TET1 Promotes Bladder Cancer Cell Proliferation and Invasion by Reducing DNA Hydroxymethylation of AJAP1 期刊论文 FRONTIERS IN ONCOLOGY, 2020, 卷号: 10, 页码: 16 作者:  Yan, Yi-lin;  Huang, Zheng-nan;  Zhu, Zhen;  Cui, Yang-yan;  Li, Mei-qian 收藏  |  浏览/下载：84/0  |  提交时间：2020/12/24 ten-eleven translocation 1 (TET1)  DNA methylation  bladder cancer  vitamin C  adherens junction-associated protein 1 (AJAP1)   Synthesis and biological investigation of triazolopyridinone derivatives as potential multireceptor atypical antipsychotics 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 8, 页码: 6 作者:  Shi, Wenqiang 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 Triazolopyridinone  Antipsychotic  Multireceptor  5-HT1A receptor   Identification of glycogene-type and validation of ST3GAL6 as a biomarker predicts clinical outcome and cancer cell invasion in urinary bladder cancer 期刊论文 THERANOSTICS, 2020, 卷号: 10, 期号: 22, 页码: 10078-10091 作者:  Dalangood, Sumiya;  Zhu, Zhen;  Ma, Zhihui;  Li, Jiaxuan;  Zeng, Qinghe 收藏  |  浏览/下载：15/0  |  提交时间：2020/12/24 glycogene  ST3GAL6  urinary bladder cancer  clinical outcome  invasion   Sub-anesthetic and anesthetic ketamine produce different long-lasting behavioral phenotypes (24 h post-treatment) via inducing different brain derived neurotrophic factor (BDNF) expression level in the hippocampus 期刊论文 NEUROBIOLOGY OF LEARNING AND MEMORY, 2020, 卷号: 167, 页码: 10 作者:  Wu, Chunhui;  Wang, Yu;  He, Yang;  Wu, Song;  Xie, Zhifei 收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 Ketamine  Sub-anesthetic dose  Anesthetic dose  Depression  Cognition  Anxiety