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科研机构
上海药物研究所 [27]
内容类型
期刊论文 [27]
发表日期
2021 [3]
2020 [3]
2019 [3]
2018 [1]
2017 [3]
2016 [1]
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Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of M1 and T cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Lu, Qiu-kai
;
Fan, Chen
;
Xiang, Cai-gui
;
Wu, Bing
;
Lu, Hui-min
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/06/11
PDE4
apremilast
skin fibrosis
macrophages
Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury
期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 7, 页码: 925-941
作者:
Liu, Yanjun
;
Li, Jiacheng
;
Liao, Liping
;
Huang, Heming
;
Fan, Shijie
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/08/17
Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-beta RI/Smad Signaling
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 6, 页码: 19
作者:
Luo, Xin
;
Deng, Qiangqiang
;
Xue, Yaru
;
Zhang, Tianwei
;
Wu, Zhitao
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/06/11
pulmonary fibrosis
bleomycin
magnesium lithospermate B
transforming growth factor-beta
Smad signaling
Transcriptional and proteomic insights into the host response in fatal COVID-19 cases
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 45, 页码: 28336-28343
作者:
Wu, Meng
;
Chen, Yaobing
;
Xia, Han
;
Wang, Changli
;
Tan, Chin Yee
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/12/24
COVID-19
SARS-CoV-2
neutrophil
fibrosis
NETosis
Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis
期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 4, 页码: 17
作者:
Li, Heng
;
Feng, Chunlan
;
Fan, Chen
;
Yang, Yang
;
Yang, Xiaoqian
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
Preparation and evaluation of PEGylated asiatic acid nanostructured lipid carriers on anti-fibrosis effects
期刊论文
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2020, 卷号: 46, 期号: 1, 页码: 57-69
作者:
Chen, Xiaoxiao
;
Zhang, Yawen
;
Zhao, Pengfei
;
Chen, Yan
;
Zhou, Yunli
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
Asiatic acid
PEGylated nanostructured lipid carriers
anti-liver fibrosis
liver targeting strategy
pharmacokinetics
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15
作者:
Zhang, Zongwang
;
Wu, Yanwei
;
Wu, Bing
;
Qi, Qing
;
Li, Heng
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Systemic sclerosis
SAHH inhibitor
Fibrosis
Inflammation
Vasculopathy
TGF-beta
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal -actinin-4 expression and stabilizing integrin-cytoskeleton linkage
期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 页码: 16
作者:
He, Shijun
;
Liu, Xing
;
Lin, Zemin
;
Liu, Yuting
;
Gu, Lei
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
SAHH inhibitor
Lupus nephritis
-Actinin-4
Integrin-linked kinase
Integrin
Focal adhesion
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage
期刊论文
Arthritis Research & Therapy, 2019, 卷号: 21, 期号: 1
作者:
He,Shijun
;
Liu,Xing
;
Lin,Zemin
;
Liu,Yuting
;
Gu,Lei
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/07/01
SAHH inhibitor
Lupus nephritis
α-Actinin-4
Integrin-linked kinase
Integrin
Focal adhesion
AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue
期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9
作者:
Wu, Lingyan
;
Zhang, Lina
;
Li, Bohan
;
Jiang, Haowen
;
Duan, Yanan
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
AMP-activated protein kinase
thermogenesis
energy metabolism
A-769662
white adipose browning
PGC-1 alpha
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