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CORC

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Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载：40/0  |  提交时间：2022/01/04
DCZ3301, a novel aryl-guanidino inhibitor, induces cell apoptosis and cell cycle arrest via suppressing the PI3K/AKT pathway in T-cell leukemia/lymphoma 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 7, 页码: 643-650
作者:  Xiao, Wenqin;  Li, Bo;  Sun, Xi;  Yu, Dandan;  Xie, Yongsheng
收藏  |  浏览/下载：82/0  |  提交时间：2019/01/08
A11, a novel diaryl acylhydrazone derivative, exerts neuroprotection against ischemic injury in vitro and in vivo 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Feng, Hong-Xuan;  Li, Chun-Pu;  Shu, Shuang-Jie;  Liu, Hong;  Zhang, Hai-Yan
收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08
dcz3301anovelarylguanidinoinhibitorinducescellapoptosisandcellcyclearrestviasuppressingthepi3kaktpathwayintcellleukemialymphoma 期刊论文
actabiochimicaetbiophysicasinica, 2018, 卷号: 50, 期号: 7, 页码: 643
作者:  Xiao Wenqin;  Li Bo;  Sun Xi;  Yu Dandan;  Xie Yongsheng
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01
SAR study of 5-alkynyl substituted quinazolin-4(3H)-ones as phosphoinositide 3-kinase delta (PI3K delta) inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 1156-1171
作者:  Wei, Manman;  Zhang, Xi;  Wang, Xiang;  Song, Zilan;  Ding, Jian
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Cyclic helix B peptide inhibits ischemia reperfusion-induced renal fibrosis via the PI3K/Akt/FoxO3a pathway 期刊论文
Journal of Translational Medicine, 2015, 卷号: 13
作者:  Yang, Cheng;  Cao, Ye;  Zhang, Yi;  Li, Long;  Xu, Ming
收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08
CAMK1 Phosphoinositide Signal-Mediated Protein Sorting and Transport Network in Human Hepatocellular Carcinoma (HCC) by Biocomputation 期刊论文
CELL BIOCHEMISTRY AND BIOPHYSICS, 2014, 卷号: 70, 期号: 2, 页码: 1011-1016
作者:  Wang, Lin;  Huang, Juxiang;  Jiang, Minghu;  Chen, Qingchun;  Jiang, Zhenfu
收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08
Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries 期刊论文
Biochemical pharmacology, 2014, 卷号: 88, 期号: 1, 页码: 66-74
作者:  Shen, Kaikai;  Leung, Susan W S;  Ji, Lili;  Huang, Yu;  Hou, Maoqi
收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08
Discovery of the Novel mTOR Inhibitor and Its Antitumor Activities In Vitro and In Vivo 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2013, 卷号: 12, 期号: 6, 页码: 950-958
作者:  Xie, Hua;  Lee, Mee-Hyun
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08
WJD008, a Dual Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin Inhibitor, Prevents PI3K Signaling and Inhibits the Proliferation of Transformed Cells with Oncogenic PI3K Mutant 期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2010, 卷号: 334, 期号: 3, 页码: 830-838
作者:  Li, Ting;  Wang, Jia;  Wang, Xiang;  Yang, Na;  Chen, Si-meng
收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08

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