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科研机构
上海药物研究所 [59]
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期刊论文 [59]
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2021 [1]
2020 [5]
2019 [3]
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Supramolecular Antagonists Promote Mitochondrial Dysfunction
期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 13, 页码: 5730-5737
作者:
Li, Mingming
;
Song, Yanqiu
;
Song, Na
;
Wu, Guangyao
;
Zhou, Hao
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2021/08/17
Self-Assembly
Peptides
Drug Delivery
Mitochondrion-Targeting
Antagonists
Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice
期刊论文
ISCIENCE, 2020, 卷号: 23, 期号: 10, 页码: 56
作者:
Xu, Xiaoju
;
Xu, Xu
;
Hao, Yanping
;
Zhu, Xialin
;
Lu, Jian
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
DW14006 as a Direct AMPK alpha Activator Ameliorates Diabetic Peripheral Neuropathy in Mice
期刊论文
DIABETES, 2020, 卷号: 69, 期号: 9, 页码: 1974-1988
作者:
Xu, Xu
;
Wang, Wei
;
Wang, Zhengyu
;
Lv, Jianlu
;
Xu, Xiaoju
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
Dependence of PINK1 accumulation on mitochondrial redox system
期刊论文
AGING CELL, 2020, 页码: 14
作者:
Gao, Feng
;
Zhang, Yan
;
Hou, Xiaoou
;
Tao, Zhouteng
;
Ren, Haigang
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/12/24
autophagy
mitochondrion
mitophagy
neurodegenerative diseases
PINK1
Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:
Xu, Ming-ming
;
Ryan, Philip
;
Rudrawar, Santosh
;
Quinn, Ronald J.
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
advancesinthedevelopmentofimagingprobesandaggregationinhibitorsforalphasynuclein
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 483
作者:
Xu Mingming
;
Ryan Philip
;
Rudrawar Santosh
;
Quinn Ronald J
;
Zhang Haiyan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Parkinson’s disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
Metabolic characterization of diabetic retinopathy: An H-1-NMR-based metabolomic approach using human aqueous humor
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 174, 页码: 414-421
作者:
Jin, Huiyi
;
Zhu, Bijun
;
Liu, Xia
;
Jin, Jing
;
Zou, Haidong
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Metabolomics
NMR analysis
Aqueous humor
Diabetic retinopathy
Metabolite-metabolite correlation
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:
Zhou, Ting-ting
;
Zhao, Tong
;
Ma, Fei
;
Zhang, Yi-nan
;
Jiang, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
type 2 diabetes mellitus
hepatic gluconeogenesis
AMPK signaling pathway
(E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)
4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)
prodrug
a11anoveldiarylacylhydrazonederivativeexertsneuroprotectionagainstischemicinjuryinvitroandinvivo
期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 2, 页码: 160
作者:
Feng Hongxuan
;
Li Chunpu
;
Shu Shuangjie
;
Liu Hong
;
Zhang Haiyan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
FOCAL CEREBRAL-ISCHEMIA
OXIDATIVE STRESS
DRUG DISCOVERY
COLORIMETRIC ASSAY
TREAT STROKE
MECHANISMS
DISEASE
OXYGEN
PROTECTS
MODELS
ischemic stroke
neuroprotection
diaryl acylhydrazone
oxygen glucose deprivation
middle cerebral artery occlusion
protein kinase B
extracellular signal-regulated kinase
The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 11, 页码: 3403-3414
作者:
Lu, Yao
;
Ma, Jiang
;
Song, Zijing
;
Ye, Yang
;
Fu, Peter P.
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid
Retrorsine
ATP5B
Mitochondrial damage
Pyrrole-protein adduct
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