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科研机构
上海药物研究所 [69]
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期刊论文 [68]
会议论文 [1]
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2021 [3]
2020 [2]
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Chemistry [6]
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Absorption, distribution, metabolism, and excretion of [C-14]NBP (3-n-butylphthalide) in rats
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 9
作者:
Tian, Junjun
;
Lei, Peng
;
He, Yifei
;
Zhang, Ning
;
Ge, Xinyu
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
3-n-butylphthalide (NBP)
[C-14]NBP
Pharmacokinetics
Tissue distribution
Metabolism
Mass balance
Characterization and quantitative determination of henagliflozin metabolites in humans
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 192, 页码: 8
作者:
Chen, Zhendong
;
Li, Liang
;
Zhan, Yan
;
Zhang, Yifan
;
Liu, Haiyan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Henagliflozin
Metabolism
LC-MS/MS
Pyrrolidinyl Synthetic Cathinones alpha-PHP and 4F-alpha-PVP Metabolite Profiling Using Human Hepatocyte Incubations
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 1, 页码: 17
作者:
Carlier, Jeremy
;
Diao, Xingxing
;
Giorgetti, Raffaele
;
Busardo, Francesco P.
;
Huestis, Marilyn A.
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/05/24
alpha-PHP
PV7
4F-alpha-PVP
novel psychoactive substance
synthetic cathinone
bath salt
hepatocyte metabolism
liquid chromatography-high resolution tandem mass spectrometry
Comparison of intramuscular and intravenous pharmacokinetics of ginsenosides in humans after dosing XueShuanTong, a lyophilized extract of Panax notoginseng roots
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 253, 页码: 7
作者:
Zhang, Hai-Yan
;
Niu, Wei
;
Olaleye, Olajide E.
;
Du, Fei-Fei
;
Wang, Feng-Qing
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
Ginsenoside
Pharmacokinetics
Intramuscular
Intravascular
XueShuanTong
Panay notoginseng roots
Sanqi
The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor
期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 45, 期号: 1, 页码: 15-26
作者:
Zhang, Leduo
;
Mao, Yu
;
Gao, Zhiwei
;
Chen, Xiaoyan
;
Li, Xin
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:
Pan, Lulu
;
Guo, Shuang
;
Chen, Xiaoyan
;
Jiang, Xiangrui
;
Shen, Jingshan
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/07/01
TPNI71
Metabolism
UPLC/Q-TOF MS
High-resolution mass spectrometry
Metabolite identification
Rapid structure identification of nineteen metabolites of ondansetron in human urine using LC/MSn
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2019, 页码: 7
作者:
Duan, Mingyu
;
Qin, Li
;
Zhong, Dafang
;
Zhang, Peng
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
human metabolism
LC
MSn
metabolic pathways
ondansetron
New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites
期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 15
作者:
Diao, Xingxing
;
Huestis, Marilyn A.
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
novel psychoactive substances
NPS
synthetic cannabinoid
SC
metabolism
urinary metabolites
hepatocyte incubation
metabolismanddispositionofpyrotinibinhealthymalevolunteerscovalentbindingwithhumanplasmaprotein
期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 7, 页码: 980
作者:
Meng Jian
;
Liu Xiaoyun
;
Ma Sheng
;
Zhang Hua
;
Yu Songda
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2020/07/01
pyrotinib
EGFR/HER2 dual tyrosine kinase inhibitor
breast cancer
drug metabolism
drug disposition
human plasma
covalent binding
chemicalcocktailsenablehepaticreprogrammingofhumanurinederivedcellswithasingletranscriptionfactor
期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 5, 页码: 620
作者:
Tang Wei
;
Guo Ren
;
Shen Shijun
;
Zheng Yang
;
Lu Yuting
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
ACUTE LIVER-FAILURE
PLURIPOTENT STEM-CELLS
HEPATOCYTE-LIKE CELLS
MOUSE FIBROBLASTS
GENE-EXPRESSION
TRANSPLANTATION
GENERATION
MAINTENANCE
METABOLISM
DISEASE
reprogramming
hepatic transdifferentiation
human urine-derived cells
chemical cocktail
regenerative medicine
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