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Alzheimer's disease hypothesis and related therapies 期刊论文
TRANSLATIONAL NEURODEGENERATION, 2018, 卷号: 7
作者:  Du, Xiaoguang;  Wang, Xinyi;  Geng, Meiyu
收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08
Defining the minimum substrate and charge recognition model of gamma-secretase 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 10, 页码: 1412-1424
作者:  Yan, Yan;  Xu, Ting-Hai;  Melcher, Karsten;  Xu, H. Eric
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the gamma - secretase cleavage sites 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 38, 页码: 15826-15837
作者:  Yan, Yan;  Xu, Ting-Hai;  Harikumar, Kaleeckal G.;  Miller, Laurence J.;  Melcher, Karsten
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Research advances in the treatment of Alzheimer's disease with polysaccharides from traditional Chinese medicine 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 9, 页码: 641-652
作者:  Liu Qin;  Wang Shun-Chun;  Ding Kan
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Amyloid beta: structure, biology and structure-based therapeutic development 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 9, 页码: 1205-1235
作者:  Chen, Guo-fang;  Xu, Ting-hai;  Yan, Yan;  Zhou, Yu-ren;  Jiang, Yi
收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
amyloidbetastructurebiologyandstructurebasedtherapeuticdevelopment 期刊论文
actapharmacologicasinica, 2017, 卷号: 38, 期号: 9, 页码: 1205
作者:  Chen Guofang;  Xu Tinghai;  Yan Yan;  Zhou Yuren;  Jiang Yi
收藏  |  浏览/下载:49/0  |  提交时间:2020/07/01
Alzheimer's disease-associated mutations increase amyloid precursor protein resistance to gamma-secretase cleavage and the A beta 42/A beta 40 ratio 期刊论文
CELL DISCOVERY, 2016, 卷号: 2
作者:  Xu, Ting-Hai;  Yan, Yan;  Kang, Yanyong;  Jiang, Yi;  Melcher, Karsten
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
The cryo-electron microscopy structure of gamma-secretase: towards complex assembly, substrate recognition and a catalytic mechanism 期刊论文
NATIONAL SCIENCE REVIEW, 2015, 卷号: 2, 期号: 1, 页码: 4-5
作者:  Kang, Yanyong;  Melcher, Karsten;  Xu, H. Eric
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08
Targeting the gamma-/beta-secretase interaction reduces beta-amyloid generation and ameliorates Alzheimer's disease-related pathogenesis 期刊论文
CELL DISCOVERY, 2015, 卷号: 1
作者:  Cui, Jin;  Wang, Xiaoyin;  Li, Xiaohang;  Wang, Xin;  Zhang, Chenlu
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Smart Soup, a Traditional Chinese Medicine Formula, Ameliorates Amyloid Pathology and Related Cognitive Deficits 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 11
作者:  Hou, Yujun;  Wang, Ying;  Zhao, Jian;  Li, Xiaohang;  Cui, Jin
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08


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