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浏览/检索结果: 共9条，第1-9条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2 期刊论文 CELL RESEARCH, 2021, 页码: 3 作者:  Xie, Yuanchao;  Yin, Wanchao;  Zhang, Yumin;  Shang, Weijuan;  Wang, Zhen 收藏  |  浏览/下载：108/0  |  提交时间：2021/11/04 A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Ren, Peng-xuan;  Shang, Wei-juan;  Yin, Wan-chao;  Ge, Huan;  Wang, Lin 收藏  |  浏览/下载：85/0  |  提交时间：2021/06/11 SARS-CoV-2 inhibitors  RdRp  host ribosome  Virus RNA   Weinreb Amide Approach to the Practical Synthesis of a Key Remdesivir Intermediate 期刊论文 JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 7, 页码: 5065-5072 作者:  Xie, Yuanchao;  Hu, Tianwen;  Zhang, Yan;  Wei, Daibao;  Zheng, Wei 收藏  |  浏览/下载：23/0  |  提交时间：2021/08/17 Significant Inhibition of Porcine Epidemic Diarrhea Virus In Vitro by Remdesivir, Its Parent Nucleoside and beta-d-N-4-hydroxycytidine 期刊论文 VIROLOGICA SINICA, 2021, 页码: 9 作者:  Xie, Yuanchao;  Guo, Xiaozhen;  Hu, Tianwen;  Wei, Daibao;  Ma, Xiuli 收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24 Porcine epidemic diarrhea virus (PEDV)  Nucleoside analog  RNA dependent RNA polymerase (RdRp)  Antiviral activity   Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin 期刊论文 NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2021, 页码: 21 作者:  Yin, Wanchao;  Luan, Xiaodong;  Li, Zhihai;  Zhou, Ziwei;  Wang, Qingxing 收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24 Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC-MS/MS 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 194, 页码: 10 作者:  Hu, Wenjuan;  Chang, Lu;  Ke, Changqiang;  Xie, Yuanchao;  Shen, Jingshan 收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24 Remdesivir  Nucleotide monophosphate  Nucleotide triphosphate  Stability  Recovery  LC-MS/MS   RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19 期刊论文 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 卷号: 538, 页码: 47-53 作者:  Jiang, Yi;  Yin, Wanchao;  Xu, H. Eric 收藏  |  浏览/下载：32/0  |  提交时间：2021/05/24 COVID-19  SARS-CoV-2  RNA-dependent RNA polymerase  Structure  RNA recognition  Remdesivir   Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 6 作者:  Hu, Wen-juan;  Chang, Lu;  Yang, Ying;  Wang, Xin;  Xie, Yuan-chao 收藏  |  浏览/下载：49/0  |  提交时间：2020/12/21 remdesivir  pharmacokinetics  tissue distribution  nucleotide monophosphate  nucleotide triphosphate  nucleoside   Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文 SCIENCE, 2020, 卷号: 368, 期号: 6498, 页码: 1499-+ 作者:  Yin, Wanchao;  Mao, Chunyou;  Luan, Xiaodong;  Shen, Dan-Dan;  Shen, Qingya 收藏  |  浏览/下载：57/0  |  提交时间：2020/12/24