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科研机构
上海药物研究所 [33]
内容类型
期刊论文 [33]
发表日期
2021 [6]
2020 [4]
2019 [2]
2018 [5]
2017 [4]
2016 [1]
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Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGF beta signaling
期刊论文
ONCOGENE, 2021, 页码: 10
作者:
Kong, Ya
;
Zhang, Yutian
;
Wang, Hanlin
;
Kan, Weijuan
;
Guo, Haoran
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/01/04
Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:
Fan, Shijie
;
Yue, Liyan
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2021/12/16
covalent modification
probes
proteome
LC3
post-translational modification
Ligand-based approach for predicting drug targets and for virtual screening against COVID-19
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 2, 页码: 1053-1064
作者:
Yang, Yanqing
;
Zhu, Zhengdan
;
Wang, Xiaoyu
;
Zhang, Xinben
;
Mu, Kaijie
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/11/16
D3Similarity
COVID-19
target prediction
database
virtual screening
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:
Zhang, Ning
;
Tian, Yu-Nan
;
Zhou, Li-Na
;
Li, Meng-Zhu
;
Chen, Hua-Dong
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma
期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403
作者:
Wang, Jianfeng
;
Wang, Chen
;
Xu, Pan
;
Li, Xiao
;
Lu, Yongning
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2021/05/24
clear cell renal cell carcinoma
protein arginine methyltransferase 1
therapeutic
lipocalin2 (LCN2)
sunitinib
Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
Cell Death & Disease, 2021, 卷号: 12, 期号: 2, 页码: 1
作者:
Ning Zhang
;
Yu-Nan Tian
;
Li-Na Zhou
;
Meng-Zhu Li
;
Hua-Dong Chen
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/12/01
Structural basis for activation of the growth hormone-releasing hormone receptor
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10
作者:
Zhou, Fulai
;
Zhang, Huibing
;
Cong, Zhaotong
;
Zhao, Li-Hua
;
Zhou, Qingtong
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/21
Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-Dependent TFEB Signaling Pathway
期刊论文
CIRCULATION RESEARCH, 2020, 卷号: 127, 期号: 4, 页码: 534-549
作者:
You, Yan
;
Bao, Wei-Lian
;
Zhang, Su-Lin
;
Li, Hai-Dong
;
Li, Hui
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/12/24
atherosclerosis
foam cell
lipid metabolism
monocytes
sorting nexin
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
;
Fan, Ting
;
Zhu, Yuyu
收藏
  |  
浏览/下载:237/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
Integrin beta 3 Deficiency Results in Hypertriglyceridemia via Disrupting LPL (Lipoprotein Lipase) Secretion
期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2020, 卷号: 40, 期号: 5, 页码: 1296-1310
作者:
Xiao, Bing
;
Mao, Jianhua
;
Sun, Boyang
;
Zhang, Wei
;
Wang, Yun
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
integrins
lipoprotein lipase
lipoproteins
protein kinase D
thrombasthenia
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