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CORC

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Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:  Wang, Yu-xiang;  Zhang, Xu;  Ma, Qing-yang;  Hu, Lan-dian;  Zhang, Xi
收藏  |  浏览/下载：48/0  |  提交时间：2021/05/24
Emerging roles of class I PI3K inhibitors in modulating tumor microenvironment and immunity 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:  Sun, Pu;  Meng, Ling-hua
收藏  |  浏览/下载：40/0  |  提交时间：2020/12/21
Design, synthesis, and biological evaluation of thieno[3,2-d]pyrimidine derivatives as potential simplified phosphatidylinositol 3-kinase alpha inhibitors 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 94, 期号: 6, 页码: 2013-2022
作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Wang, Yi;  Song, Kun
收藏  |  浏览/下载：75/0  |  提交时间：2020/07/01
High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822
作者:  Wang, Jia;  Gong, Grace Qun;  Zhou, Yan;  Lee, Woo-Jeong;  Buchanan, Christina Maree
收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08
Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia
收藏  |  浏览/下载：87/0  |  提交时间：2019/01/08
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5, 页码: 767-771
作者:  Basnet, Rajesh;  Gong, Grace Qun;  Li, Chenyao;  Wang, Ming-Wei
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08
Dihydroartemisinin selectively inhibits PDGFR alpha-positive ovarian cancer growth and metastasis through inducing degradation of PDGFR alpha protein 期刊论文
CELL DISCOVERY, 2017, 卷号: 3
作者:  Li, Xiaoguang;  Ba, Qian;  Liu, Yanling;  Yue, Qingxi;  Chen, Peizhan
收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08
Discovery of a Novel Series of 7-Azaindole Scaffold Derivatives as PI3K Inhibitors with Potent Activity 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 8, 页码: 875-880
作者:  Yang, Chengbin;  Zhang, Xi;  Wang, Yi;  Yang, Yongtai;  Liu, Xiaofeng
收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08
Puquitinib, a novel orally available PI3K inhibitor, exhibits potent antitumor efficacy against acute myeloid leukemia 期刊论文
CANCER SCIENCE, 2017, 卷号: 108, 期号: 7, 页码: 1476-1484
作者:  Xie, Chengying;  He, Ye;  Zhen, Mingyue;  Wang, Yulan;  Xu, Yongping
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08

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