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科研机构
上海药物研究所 [39]
内容类型
期刊论文 [39]
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2021 [4]
2020 [5]
2019 [5]
2018 [7]
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Signaling profiles in HEK 293T cells co-expressing GLP-1 and GIP receptors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 8
作者:
Wang, Yu-zhe
;
Yang, De-hua
;
Wang, Ming-wei
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/11/04
glucagon-like peptide-1 receptor
glucose-dependent insulinotropic peptide receptor
peptide 19
LY3298176
heteromerization
type 2 diabetes
Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2021, 页码: 14
作者:
Duan, Nianxiu
;
Li, Junjun
;
Song, Sha
;
Wang, Feng
;
Yang, Yiwei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
drug delivery
pancreatic cancer
prodrugs
smart liposomes
tumor-specific vascular promotion
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 213, 页码: 17
作者:
Xiao, Xuanzheng
;
Lai, Mengzhen
;
Song, Zilan
;
Geng, Meiyu
;
Ding, Jian
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/05/24
KRAS
Covalent inhibitor
Pyridopyrimidinone
Antiproliferative effect
Scaffold hopping
Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer
期刊论文
ADVANCED SCIENCE, 2021, 页码: 12
作者:
Sun, Fang
;
Zhu, Qiurong
;
Li, Tianliang
;
Saeed, Madiha
;
Xu, Zhiai
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/05/24
glucose metabolism
immunogenic cell death
pancreatic cancer
photoimmunotherapy
prodrug nanoparticles
A pectin-like polysaccharide from Polygala tenuifolia inhibits pancreatic cancer cell growth in vitro and in vivo by inducing apoptosis and suppressing autophagy
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 107-115
作者:
Bian, Youcheng
;
Zeng, Hui
;
Tao, Hong
;
Huang, Lulin
;
Du, Zhenyun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/12/24
Polygala tenuifolia
Pectin
Pancreatic cancer
Apoptosis
Autophagy
MT1-MMP-Activated Liposomes to Improve Tumor Blood Perfusion and Drug Delivery for Enhanced Pancreatic Cancer Therapy
期刊论文
ADVANCED SCIENCE, 2020, 页码: 14
作者:
Wei, Yan
;
Song, Sha
;
Duan, Nianxiu
;
Wang, Feng
;
Wang, Yuxi
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2020/12/24
membrane type 1-matrix metalloproteinase-activated cilengitide
pancreatic cancer
smart liposomes
vascular promotion
Cordycepin inhibits pancreatic cancer cell growth in vitro and in vivo via targeting FGFR2 and blocking ERK signaling
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2020, 卷号: 18, 期号: 5, 页码: 345-355
作者:
Li Xue-Ying
;
Tao Hong
;
Jin Can
;
Du Zhen-Yun
;
Liao Wen-Feng
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Cordycepin
FGFR2
Apoptosis
Pancreatic cancer
Ras/Erk
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors
期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:
Chen, Hua-Dong
;
Guo, Ne
;
Song, Shan-Shan
;
Chen, Chuan-Huizi
;
Miao, Ze-Hong
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/12/24
PARP inhibitors resistance
BRCA2
COX-2
BIRC3
apoptotic resistance
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors
期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:
Chen, Hua-Dong
;
Guo, Ne
;
Song, Shan-Shan
;
Chen, Chuan-Huizi
;
Miao, Ze-Hong
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/12/24
PARP inhibitors resistance
BRCA2
COX-2
BIRC3
apoptotic resistance
Isolation and structural characterization of a pectin from Lycium ruthenicum Murr and its anti-pancreatic ductal adenocarcinoma cell activity
期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 223, 页码: 10
作者:
Zhang, Shihai
;
He, Fei
;
Chen, Xia
;
Ding, Kan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Rhamnogalacturonan I (RG-I)
Polysaccharide
Lycium ruthenicum Murr
Pancreatic cancer
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