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科研机构
上海药物研究所 [27]
内容类型
期刊论文 [26]
会议论文 [1]
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2021 [1]
2019 [1]
2018 [2]
2017 [4]
2016 [4]
2015 [1]
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TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia
期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 378, 期号: 1, 页码: 20-30
作者:
Wang, Yu
;
He, Yang
;
Yang, Feipu
;
Abame, Melkamu Alemu
;
Wu, Chunhui
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/11/04
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice
A Novel 2-Phenylamino-Quinazoline-Based Compound Expands the Neural Stem Cell Pool and Promotes the Hippocampal Neurogenesis and the Cognitive Ability of Adult Mice
期刊论文
STEM CELLS, 2018, 卷号: 36, 期号: 8, 页码: 1273-1285
作者:
Lu, Hui
;
Cheng, Gang
;
Hong, Feng
;
Zhang, Lei
;
Hu, Youhong
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
Neural stem cells
Notch signaling pathway
Hes5
Adult hippocampal neurogenesis
Learning and memory
2-phenylamino-quinazoline
Analogous β-Carboline Alkaloids Harmaline and Harmine Ameliorate Scopolamine-Induced Cognition Dysfunction by Attenuating Acetylcholinesterase Activity, Oxidative Stress, and Inflammation in Mice
期刊论文
Frontiers in pharmacology, 2018, 卷号: 9, 页码: 346
作者:
Li, Shu-Ping
;
Wang, Yu-Wen
;
Qi, Sheng-Lan
;
Zhang, Yun-Peng
;
Deng, Gang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 8, 页码: 1104-1119
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
;
Wang, Yi-yang
;
Xu, Xin
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Alzheimer's disease
LX2343
cognitive deficits
oxidative stress
tauopathy
mitochondria
GSK-3 beta inhibitor
neuroprotection
ICV-STZ rats
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both A beta and Tau pathologies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 1, 页码: 9-28
作者:
Li, Cong
;
Gu, Xiao-dan
;
Lei, Min
;
Wu, Jia-yi
;
Jin, Jia-zhen
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-beta
Tau
autophagy
BACE1
GSK3 beta
PI3K
thamnoliavermicularisextractimproveslearningabilityinappps1transgenicmicebyamelioratingbothaandtaupathologies
期刊论文
actapharmacologicasinica, 2017, 卷号: 38, 期号: 1, 页码: 9
作者:
Li Cong
;
Guo Xiaodan
;
Lei Min
;
Wu Jiayi
;
Jin Jiazhen
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-β
Tau
autophagy
BACE1
GSK3β
PI_3K
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both Aβ and Tau pathologies
期刊论文
Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 1, 页码: 9
作者:
Li Cong
;
Guo Xiaodan
;
Lei Min
;
Wu Jiayi
;
Jin Jiazhen
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/12/24
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-β
Tau
autophagy
BACE1
GSK3β
PI_3K
Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
;
Xu, Xin
;
Zhu, Zhi-yuan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Alzheimer's disease
N-(1,3-benzodioxol-5-yl)-2-[5-chloro-2-methoxy(phenylsulfonyl)anilino]acetamide (LX2343)
streptozotocin
amyloid beta
BACE1
PI3K
autophagy
APP/PS1 transgenic mice
cognitive deficit
The sphingosine-1-phosphate analogue, FTY-720, promotes the proliferation of embryonic neural stem cells, enhances hippocampal neurogenesis and learning and memory abilities in adult mice
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2016, 卷号: 173, 期号: 18, 页码: 2793-2807
作者:
Sun, Yili
;
Hong, Feng
;
Zhang, Lei
;
Feng, Linyin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
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