×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [37]
内容类型
期刊论文 [37]
发表日期
2021 [3]
2020 [1]
2018 [3]
2017 [2]
2016 [1]
2013 [3]
更多...
学科主题
Chemistry [2]
Biochemist... [1]
Pharmacolo... [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共37条,第1-10条
帮助
限定条件
专题:上海药物研究所
第一署名单位
第一作者单位
通讯作者单位
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Yong-Mei
;
Ye, Lu-Yu
;
Li, Tian-Yu
;
Guo, Fan
;
Guo, Fei
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/04
YL-0919
medial prefrontal cortex
GABAergic neurons
5-HT1A receptor
GAD67-GFP transgenic mice
disinhibition
fluoxetine
electrophysiological recording
Fast determination of 16 circulating neurotransmitters and their metabolites in plasma samples of spontaneously hypertensive rats intervened with five different Uncaria
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1179, 页码: 9
作者:
Gao, Lei
;
Zhang, Zijia
;
Feng, Zijin
;
Wei, Wenlong
;
Wu, Wenyong
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
Neurotransmitters
LC-MS
Hypertension
Uncaria
Spontaneously hypertensive rats
Small-molecule fluorescence-based probes for interrogating major organ diseases
期刊论文
CHEMICAL SOCIETY REVIEWS, 2021, 页码: 39
作者:
Han, Hai-Hao
;
Tian, He, Jr.
;
Zang, Yi
;
Sedgwick, Adam C.
;
Li, Jia
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/08/17
Recent advances in dopaminergic strategies for the treatment of Parkinson's disease
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Mao, Qi
;
Qin, Wang-zhi
;
Zhang, Ao
;
Ye, Na
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Parkinson's disease
dopamine
D-1 receptor
D-2 receptor
allosteric modulator
neuroprotection
multitarget
drug discovery and development
neurodegenerative diseases
Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer's Disease Agents
期刊论文
ACS chemical neuroscience, 2018
作者:
Xu, Yixiang
;
Zhang, Jian
;
Wang, Huan
;
Mao, Fei
;
Bao, Keting
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345
作者:
Mao, Fei
;
Wang, Huan
;
Ni, Wei
;
Zheng, Xinyu
;
Wang, Manjiong
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
Alzheimer's disease
drug repositioning
dual-target inhibitor
AChE inhibition
PDE5 inhibition
Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 143, 页码: 33-47
作者:
Xu, Yi-xiang
;
Wang, Huan
;
Li, Xiao-kang
;
Dong, Sheng-nan
;
Liu, Wen-wen
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Multifunctional agents
AChE inhibitors
MAO-B inhibitors
Metal chelating agents
Alzheimer's disease
Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 101-112
作者:
Ji, Yue-Yang
;
Lin, Sen-Dong
;
Wang, Yu-Jie
;
Su, Ming-Bo
;
Zhang, Wei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Tranylcypromine
LSD1
Stereoselective cyclopropanation
Chiral synthesis
MAO-A
MAO-B
Research advances in non-P450-mediated drug oxidative metabolism
期刊论文
Acta Pharmaceutica Sinica, 2017, 卷号: 52, 期号: 1, 页码: 8-18
作者:
Zhou Lei
;
Zhong Dafang
;
Chen Xiaoyan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
flavin-containing monooxygenase
monoamine oxidase
aldehyde oxidase
xanthine oxidase
alcohol dehydrogenase
aldehyde dehydrogenase
oxidative metabolism
Development of Novel Alkoxyisoxazoles as Sigma-1 Receptor Antagonists with Antinociceptive Efficacy
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 13, 页码: 6329-6343
作者:
Sun, Hao
;
Shi, Min
;
Zhang, Wei
;
Zheng, Yue-Ming
;
Xu, Ya-Zhou
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
©版权所有 ©2017 CSpace - Powered by
CSpace