×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [31]
内容类型
期刊论文 [31]
发表日期
2021 [3]
2020 [3]
2019 [3]
2018 [4]
2016 [6]
2015 [2]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共31条,第1-10条
帮助
限定条件
专题:上海药物研究所
第一署名单位
第一作者单位
通讯作者单位
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 9
作者:
Chen, Yuning
;
Zhang, Ya-Nan
;
Yan, Renhong
;
Wang, Guifeng
;
Zhang, Yuanyuan
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/11/04
Liquid chromatography-mass spectrometry method for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2021, 卷号: 11, 期号: 4, 页码: 472-479
作者:
Gao, Yuxiong
;
Chen, Zhendong
;
Yang, Changyong
;
Zhong, Dafang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/11/04
Anti-sclerostin monoclonal antibody (SHR-1222)
LC-MS/MS
Anti-drug antibody
Toxicokinetic
Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2021, 页码: 20
作者:
Liu, Chenglong
;
Zhou, Feilong
;
Yan, Ziqin
;
Shen, Lian
;
Zhang, Xichen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/06/11
immunotherapy
PD-1/PD-L1
TGF-beta
tumour immune microenvironment
An antibody-drug conjugate targeting a GSTA glycosite-signature epitope of MUC1 expressed by non-small cell lung cancer
期刊论文
CANCER MEDICINE, 2020, 页码: 12
作者:
Pan, Deng
;
Tang, Yubo
;
Tong, Jiao
;
Xie, Chengmei
;
Chen, Jiaxi
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
Small-molecule PD-L1 inhibitor BMS1166 abrogates the function of PD-L1 by blocking its ER export
期刊论文
ONCOIMMUNOLOGY, 2020, 卷号: 9, 期号: 1, 页码: 11
作者:
Chen, Fang-Fang
;
Li, Zheng
;
Ma, Dawei
;
Yu, Qiang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/24
BMS1166
PD-L1
PD-1
glycosylation
ER export
Thermostability detection and optimization of glycoengineered antibodies and antibody-drug conjugates based on differential scanning flouremitry analysis
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 94, 页码: 10
作者:
Qin, Ken
;
Shi, Wei
;
Zhao, Lei
;
Li, Mingjie
;
Tang, Yubo
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/07/01
DSF
Thermostability
Glycosylation
Glyco-engineered antibodies
ADCs
Two validated liquid chromatography-mass spectrometry methods with different pretreatments for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum compared with an electrochemiluminescence method
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 175, 页码: 11
作者:
Gao, Yuxiong
;
Zhang, Dan
;
Yang, Changyong
;
Duan, Xiaotao
;
Li, Xiuli
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Anti-CD47 monoclonal antibody
LC-MS
Adsorption issue
Electrochemiluminescence
Pharmacokinetics
Cross-validation
Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses
期刊论文
CELL DISCOVERY, 2019, 卷号: 5, 页码: 15
作者:
Chen, Jinhuan
;
Ye, Xiaohua
;
Zhang, Xue-Yang
;
Zhu, Zhengdan
;
Zhang, Xiang
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Small-Molecule Immuno-Oncology Therapy: Advances, Challenges and New Directions
期刊论文
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 3, 页码: 180-185
作者:
Chen, Shulun
;
Song, Zilan
;
Zhang, Ao
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
A bridging immunogenicity assay for monoclonal antibody: case study with SHR-1222
期刊论文
BIOANALYSIS, 2018, 卷号: 10, 期号: 14, 页码: 1115-1127
作者:
Zhang, Dan
;
Yang, Changyong
;
Chen, Xiaoyan
;
Li, Xiuli
;
Zhong, Dafang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
ADAs
anti-drug antibodies
bridging immunogenicity assay
monoclonal antibody (mAb)
SHR-1222
©版权所有 ©2017 CSpace - Powered by
CSpace