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科研机构
上海药物研究所 [17]
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期刊论文 [17]
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2021 [3]
2020 [1]
2018 [1]
2017 [1]
2015 [2]
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Chemistry [1]
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专题:上海药物研究所
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Neurovascular protection of salvianolic acid B and ginsenoside Rg1 combination against acute ischemic stroke in rats
期刊论文
NEUROREPORT, 2021, 卷号: 32, 期号: 13, 页码: 1140-1146
作者:
Fu, Yao
;
Xing, Rongrong
;
Wang, Linlin
;
Yang, Li
;
Jiang, Baohong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/11/04
acute ischemic stroke
ginsenoside Rg1
salvianolic acid B
Desorption electrospray ionization (DESI) source coupling ion mobility mass spectrometry for imaging fluoropezil (DC20) distribution in rat brain
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 页码: 13
作者:
Guo, Runcong
;
Zhou, Lei
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/11/04
DESI
Mass spectrometry imaging
Fluoropezil (DC20)
Brain distribution
Optimization strategy
MALDI-MS imaging of lipids and small molecules in rat brain tissue based on graphene oxide film pre-coated matrix
期刊论文
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021, 卷号: 464, 页码: 8
作者:
Xu, Yang
;
Deng, Yingzhi
;
Ye, Rongrong
;
Gong, Can
;
Liu, Zhaoxin
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/06/11
Single-layer graphene oxide film
Matrix-assisted laser desorption ionization-mass spectrometry imaging
Phospholipids
Pre-coated matrix
Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Li, Man
;
Li, Shi-chun
;
Dou, Bao-kai
;
Zou, Ying-xiang
;
Han, Hao-zhen
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
cycloastragenol
SIRT1
apoptosis
neuroinflammation
cerebral ischemia
Development and validation of a highly sensitive LC-MS/MS method for determination of brain active agent dianhydrogalactitol in mouse plasma and tissues: Application to a pharmacokinetic study
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2018, 卷号: 1087, 页码: 90-97
作者:
Sun, Lihan
;
Wu, Huajing
;
Ren, Lianjie
;
Cong, Jiaojiao
;
Qin, Xiaohui
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
1,2:5,6-dianhydrogalactitol
Derivatization
LC-MS/MS
Plasma
Tissue distribution
Glioma Dual-Targeting Nanohybrid Protein Toxin Constructed by Intein-Mediated Site-Specific Ligation for Multistage Booster Delivery
期刊论文
THERANOSTICS, 2017, 卷号: 7, 期号: 14, 页码: 3489-3503
作者:
Chen, Yingzhi
;
Zhang, Meng
;
Jin, Hongyue
;
Li, Dongdong
;
Xu, Fan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
trichosanthin
lactoferrin
brain targeted delivery
antiglioma therapy
MMP-2
intein-mediated protein ligation
cell-penetrating peptide
A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging
期刊论文
THERANOSTICS, 2015, 卷号: 5, 期号: 8, 页码: 787-795
作者:
Wang, Yaping
;
Lin, Tingting
;
Zhang, Wenyuan
;
Jiang, Yifan
;
Jin, Hongyue
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
matrix metalloprotease
protease-activatable probe
tumor imaging
brain tumor
fluorescence resonance energy transfer
Mass Spectrometry Imaging: Applications in Drug Distribution Studies
期刊论文
CURRENT DRUG METABOLISM, 2015, 卷号: 16, 期号: 9, 页码: 807-815
作者:
Zhao, Yuan-Sheng
;
Li, Chuan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Drug distribution
MALDI
Mass spectrometry imaging
metabolites
Adenosylmethionine Decarboxylase 1 (AMD1)-Mediated mRNA Processing and Cell Adhesion Activated & Inhibited Transition Mechanisms by Different Comparisons Between Chimpanzee and Human Left Hemisphere
期刊论文
CELL BIOCHEMISTRY AND BIOPHYSICS, 2014, 卷号: 70, 期号: 1, 页码: 279-288
作者:
Wang, Lin
;
Huang, Juxiang
;
Jiang, Minghu
;
Diao, Haizhen
;
Zhou, Huilei
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
mRNA processing
Cell adhesion
Adenosylmethionine decarboxylase 1 (AMD1)
Human left hemisphere
Chimpanzee left hemisphere
Sensitive assay for measurement of volatile borneol, isoborneol, and the metabolite camphor in rat pharmacokinetic study of Borneolum (Bingpian) and Borneolum syntheticum (synthetic Bingpian)
期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 10, 页码: 1337-1348
作者:
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
pharmacokinetics
borneol
isoborneol
camphor
Bingpian
liquid-liquid microextraction
gas chromatography/mass spectrometry
large-volume injection
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