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科研机构
上海药物研究所 [153]
内容类型
期刊论文 [153]
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2021 [8]
2020 [7]
2019 [11]
2018 [6]
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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Combating liver cancer through GO-targeted biomaterials
期刊论文
BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 6, 页码: 14
作者:
Huang, Xing
;
Zhang, Jiaxin
;
Song, Yijie
;
Zhang, Tong
;
Wang, Bing
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/11/04
graphene oxide
hydroxycamptothecin
anti-cancer
drug delivery system
targeting
Glycan Epitopes and Potential Glycoside Antagonists of DC-SIGN Involved in COVID-19: In Silico Study
期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 11, 页码: 16
作者:
Gao, Meina
;
Li, Hui
;
Ye, Chenghao
;
Chen, Kaixian
;
Jiang, Hualiang
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/01/04
DC-SIGN
glycan epitopes
carbohydrate recognition mechanism
natural glycoside antagonists
molecular dynamics simulations
COVID-19
Covalent sortase A inhibitor ML346 prevents Staphylococcus aureus infection of Galleria mellonella
期刊论文
RSC MEDICINAL CHEMISTRY, 2021, 页码: 12
作者:
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/12/16
Structural characteristics of Heparan sulfate required for the binding with the virus processing Enzyme Furin
期刊论文
GLYCOCONJUGATE JOURNAL, 2021, 页码: 11
作者:
Zeng, Jiaxin
;
Meng, Yuan
;
Chen, Shi-Yi
;
Zhao, Gaofeng
;
Wang, Lianchun
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2021/12/01
Furin
Heparan sulfate
Heparin
Virus infection
Carbohydrate-protein interaction
Structural insights into the activation of human calcium-sensing receptor
期刊论文
ELIFE, 2021, 卷号: 10, 页码: 24
作者:
Chen, Xiaochen
;
Wang, Lu
;
Cui, Qianqian
;
Ding, Zhanyu
;
Han, Li
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/11/04
G-protein-coupled receptor
calcium-sensing receptor
cryo-electron microscopy
calcium ions
nanobody
CaSR
GPCR
cryo-EM
None
Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma
期刊论文
CHEMICAL ENGINEERING JOURNAL, 2021, 卷号: 417, 页码: 11
作者:
Geng, Huan
;
Zhou, Mengxue
;
Li, Bin
;
Liu, Liang
;
Yang, Xu
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/08/17
Metal-drug nanoparticles
Orthotopic osteosarcoma
Osteolytic microenvironment
Zoledronate
Radiotherapy
D3DistalMutation: a Database to Explore the Effect of Distal Mutations on Enzyme Activity
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2021, 卷号: 61, 期号: 5, 页码: 2499-2508
作者:
Wang, Xiaoyu
;
Zhang, Xinben
;
Peng, Cheng
;
Shi, Yulong
;
Li, Huiyu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/08/17
Anti-inflammatory signaling through G protein-coupled receptors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Ge, Yun-jun
;
Liao, Qi-wen
;
Xu, Ye-chun
;
Zhao, Qiang
;
Wu, Bei-li
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/21
Manipulating the Click Reactivity of Dibenzoazacyclooctynes: From Azide Click Component to Caged Acylation Reagent by Silver Catalysis
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 6
作者:
Shi, Wei
;
Tang, Feng
;
Ao, Jiwei
;
Yu, Qun
;
Liu, Junjie
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/21
acylation
click chemistry
peptides
rearrangements
silver
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