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科研机构
西安交通大学 [23]
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期刊论文 [23]
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2018 [6]
2017 [3]
2016 [5]
2015 [1]
2014 [6]
2012 [1]
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专题:西安交通大学
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Sonic Hedgehog Signaling Pathway Promotes Pancreatic Cancer Pain via Nerve Growth Factor
期刊论文
PANCREAS, 2018, 卷号: 47, 页码: 1391-1391
作者:
Han, L.
;
Cheng, L.
;
Ma, Q.
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/19
Novel 4-(2-pyrimidinylamino)benzamide derivatives as potent hedgehog signaling pathway inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 页码: 5029-5036
作者:
Xin, Minhang
;
Zhang, Liandi
;
Tu, Chongxing
;
Tang, Feng
;
Wen, Jun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/19
SAR
In vivo
Hedgehog signaling pathway inhibitors
4-(2-Pyrimidinylamino)benzamide
The inhibition of heme oxygenase-1 enhances the chemosensitivity and suppresses the proliferation of pancreatic cancer cells through the SHH signaling pathway
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 52, 页码: 2101-2109
作者:
Han, Liang
;
Jiang, Jie
;
Ma, Qingyong
;
Wu, Zheng
;
Wang, Zheng
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/26
heme oxygenase-1
pancreatic cancer
sonic hedgehog
gemcitabine
Knockdown of PRMT1 suppresses IL-1 beta-induced cartilage degradation and inflammatory responses in human chondrocytes through Gli1-mediated Hedgehog signaling pathway
期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2018, 卷号: 438, 页码: 17-24
作者:
Xia, Lei
;
Zhang, Hong-Xing
;
Xing, Mei-Li
;
Xu, Yu-Ben
;
Li, Peng
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
Inflammatory responses
Osteoarthritis (OA)
PRMT1
Hedgehog/Gli-1 signaling
Cartilage degradation
Design, synthesis and biological evaluation of deuterated Vismodegib for improving pharmacokinetic properties
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 页码: 2399-2402
作者:
Wang, Fangying
;
Jiang, Hongxia
;
Deng, Yufang
;
Yu, Jiang
;
Zhan, Miao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/11/26
Basal cell carcinoma
Hedgehog signaling pathway
Deuterium-hydrogen replacement
Pharmacokinetic properties
Deuterated drug
Vismodegib
Strategies to target the Hedgehog signaling pathway for cancer therapy
期刊论文
MEDICINAL RESEARCH REVIEWS, 2018, 卷号: 38, 页码: 870-913
作者:
Xin, Minhang
;
Ji, Xinyue
;
De La Cruz, Ladie Kimberly
;
Thareja, Suresh
;
Wang, Binghe
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/26
sonidegib
hedgehog signaling pathway
Hh inhibitor
basal cell carcinoma
vismodegib
Hedgehog signaling pathway regulates the invasion of breast cancer cells via epithelial-mesenchymal transition
期刊论文
Journal of Xi'an Jiaotong University (Medical Sciences), 2017, 卷号: 38, 页码: 48-52
作者:
Ren, Hui
;
Guo, Hua
;
Chen, Ming-Wei
;
Wei, Guang-Bing
;
Fan, Lin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/26
Breast cancer
Epithelial-mesenchymal transition
Hedgehog signaling pathway
Invasion
Tumor
Introduction of fluorine to phenyl group of 4-(2-pyrimidinylamino) benzamides leading to a series of potent hedgehog signaling pathway inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 页码: 3259-3263
作者:
Xin, Minhang
;
Zhang, Liandi
;
Wen, Jun
;
Shen, Han
;
Zhao, Xinge
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/11/26
Most potent
Hedgehog signaling pathway inhibitors
4-(2-Pyrimidinylamino) benzamide scaffold
Fluorine
MicroRNA-1271 inhibits proliferation and promotes apoptosis of multiple myeloma cells through inhibiting smoothened-mediated Hedgehog signaling pathway
期刊论文
ONCOLOGY REPORTS, 2017, 卷号: 37, 页码: 1261-1269
作者:
Xu, Zhengwei
;
Huang, Chen
;
Hao, Dingjun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
cell apoptosis
cell proliferation
multiple myeloma
SMO
miR-1271
Hedgehog
Synthesis and pharmacological evaluation of trifluoromethyl containing 4-(2-pyrimidinylamino)benzamides as Hedgehog signaling pathway inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: [db:dc_citation_issue], 页码: 1079-1088
作者:
Xin, Minhang
;
Zhang, Liandi
;
Wen, Jun
;
Shen, Han
;
Liu, Zhaoyu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/02
SAR
Trifluoromethyl
Hedgehog signaling pathway inhibitors
In vivo
4-(2-Pyrimidinylamino)benzamide
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