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浏览/检索结果: 共9条，第1-9条 帮助 限定条件 专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Quantitative Determination of Flexible Pharmacological Mechanisms Based On Topological Variation in Mice Anti-Ischemic Modular Networks 其他 2016-01-01 Chen, Yin-ying; Yu, Ya-nan; Zhang, Ying-ying; Li, Bing; Liu, Jun; Li, Dong-feng; Wu, Ping; Wang, Jie; Wang, Zhong; Wang, Yong-yan 收藏  |  浏览/下载：5/0  |  提交时间：2017/12/04 PROTEIN-INTERACTION NETWORKS  DRUG DISCOVERY  CEREBRAL-ISCHEMIA  MOUSE HIPPOCAMPUS  PATHWAYS  ALLOSTERY  EXPRESSION  PREDICTION  COMPLEXES  OCCLUSION   Allostery in molecular self-assemblies: metal ions triggered self-assembly and emissions of terthiophene 期刊论文 CHEMICAL COMMUNICATIONS, 2016 Liu, Shuai; Zhao, Li; Xiao, Yunlong; Huang, Tian; Li, Jie; Huang, Jianbin; Yan, Yun 收藏  |  浏览/下载：2/0  |  提交时间：2017/12/03 DNA  FLUORESCENCE  COMPLEX  OLIGOTHIOPHENES  RECEPTORS  BEHAVIOR  NANOTUBE  BINDING  PROTEIN   Motions of Allosteric and Orthosteric Ligand-Binding Sites in Proteins are Highly Correlated 期刊论文 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2016 Ma, Xiaomin; Meng, Hu; Lai, Luhua 收藏  |  浏览/下载：14/0  |  提交时间：2017/12/04 MOLECULAR-DYNAMICS SIMULATIONS  CATABOLITE ACTIVATOR PROTEIN  TRANSCRIPTION ACTIVATION  CYTOCHROME-P450 3A4  SEQUENCE VARIATIONS  3C-LIKE PROTEINASE  RESIDUE POTENTIALS  FOLDED PROTEINS  DRUG DESIGN  DNA-BINDING   DNA Structural Correlation in Short and Long Ranges 期刊论文 JOURNAL OF PHYSICAL CHEMISTRY B, 2015 Gu, Chan; Zhang, Jun; Yang, Y. Isaac; Chen, Xi; Ge, Hao; Sun, Yujie; Su, Xiaodong; Yang, Lijiang; Xie, Sunney; Gao, Yi Qin 收藏  |  浏览/下载：3/0  |  提交时间：2017/12/03 MOLECULAR-DYNAMICS SIMULATIONS  POLYMERASE BINDING-SITE  NUCLEIC-ACID STRUCTURES  AMBER FORCE-FIELD  B-DNA  NUCLEOTIDE-SEQUENCE  ADENINE TRACT  BASE-PAIRS  PROTEIN  RNA   Protein-Protein Interface Analysis and Hot Spots Identification for Chemical Ligand Design 期刊论文 current pharmaceutical design, 2014 Chen, Jing; Ma, Xiaomin; Yuan, Yaxia; Pei, Jianfeng; Lai, Luhua 收藏  |  浏览/下载：7/0  |  提交时间：2015/11/13 Protein-protein interface analysis  small molecular binder  binding site detection  ligandability  hot spots  Pocket V.3  SMALL-MOLECULE INHIBITORS  DRUG DISCOVERY  BINDING-SITES  CONFORMATIONAL DYNAMICS  STRUCTURAL BIOLOGY  TRANSIENT POCKETS  PREDICTION  ALLOSTERY  DRUGGABILITY  MODULATION   Modeling Spatial Correlation of DNA Deformation: DNA Allostery in Protein Binding 期刊论文 journal of physical chemistry b, 2013 Xu, Xinliang; Ge, Hao; Gu, Chan; Gao, Yi Qin; Wang, Siyuan S.; Thio, Beng Joo Reginald; Hynes, James T.; Xie, X. Sunney; Cao, Jianshu 收藏  |  浏览/下载：2/0  |  提交时间：2015/11/11 ENTROPIC ELASTICITY  MISMATCH-REPAIR  SEQUENCE  SIMULATION  ENERGY   Probing Allostery Through DNA 期刊论文 science, 2013 Kim, Sangjin; Brostroemer, Erik; Xing, Dong; Jin, Jianshi; Chong, Shasha; Ge, Hao; Wang, Siyuan; Gu, Chan; Yang, Lijiang; Gao, Yi Qin; Su, Xiao-dong; Sun, Yujie; Xie, X. Sunney 收藏  |  浏览/下载：2/0  |  提交时间：2015/11/16 T7 RNA-POLYMERASE  GLUCOCORTICOID-RECEPTOR  CRYSTAL-STRUCTURE  BINDING  PROTEIN  ENDONUCLEASE  REPRESSOR  PROMOTER  OPERATOR  MODEL   Identifying Allosteric Binding Sites in Proteins with a Two-State G(o)over-bar Model for Novel Allosteric Effector Discovery 期刊论文 journal of chemical theory and computation, 2012 Qi, Yifei; Wang, Qian; Tang, Bo; Lai, Luhua 收藏  |  浏览/下载：2/0  |  提交时间：2015/11/12 LOCAL MOTIONS  D-3-PHOSPHOGLYCERATE DEHYDROGENASE  MOLECULAR-DYNAMICS  SUBSTRATE-BINDING  POPULATION-SHIFT  ENERGY LANDSCAPE  DRUG DISCOVERY  NETWORK MODEL  INHIBITION  KINASE   运用单分子技术和结构模型定量研究 DNA-蛋白质相互作用及其构象变化(英文) 其他 2012-01-01 Jianshi Jin; 苏晓东 收藏  |  浏览/下载：5/0  |  提交时间：2017/12/03 DNA  understood  conformational  affects  accessible  蛋白质相互作用  单分子  构象变化  结构模型  定量研究