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上海药物研究所 [16]
复旦大学上海医学院 [12]
厦门大学 [5]
北京大学 [5]
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期刊论文 [80]
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Potential roles of MEK1 on aging in Argopecten scallops
期刊论文
FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 16
作者:
Yuan, Ke
;
Lu, Xia
;
Ning, Junhao
;
Chen, Min
;
Wang, Quanchao
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/08/17
bivalve
Argopecten scallops
MEK1
aging
nutrition restriction
Low Temperature Plasma Suppresses Lung Cancer Cells Growth via VEGF/VEGFR2/RAS/ERK Axis
期刊论文
MOLECULES, 2022, 卷号: 27
作者:
Zhou, Yuanyuan
;
Zhang, Yan
;
Bao, Jie
;
Chen, Jinwu
;
Song, Wencheng
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/22
low temperature plasma
lung cancer cell
ROS
RNS
cell death
EPHA2 feedback activation limits the response to PDE delta inhibition in KRAS-dependent cancer cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 270-277
作者:
Chen, Yue-hong
;
Lv, Hao
;
Shen, Ning
;
Wang, Xiao-min
;
Tang, Shuai
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
KRAS
anticancer therapy
PDE delta
EPHA2
RAF
MEK
ERK signaling
Actein Inhibits Tumor Growth and Metastasis in HER2-Positive Breast Tumor Bearing Mice via Suppressing AKT/mTOR and Ras/Raf/MAPK Signaling Pathways
期刊论文
FRONTIERS IN ONCOLOGY, 2020
作者:
Wu, Xiao-Xiao
;
Yue, Grace Gar-Lee
;
Dong, Jin-Run
;
Lam, Christopher Wai-Kei
;
Wong, Chun-Kwok
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/01/05
Specific prognostic factors in hepatitis B virus-related and non-hepatitis B virus-related intrahepatic cholangiocarcinoma after macroscopic curative resection
期刊论文
JOURNAL OF SURGICAL ONCOLOGY, 2019, 卷号: 119, 期号: 1
作者:
Huang, Jianbo
;
Wang, Xiangyu
;
Zhu, Ying
;
Wang, Zheng
;
Li, Jianhua
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
hepatitis B virus
intrahepatic cholangiocarcinoma
overall survival
RAS/RAF
TP53
RDM1 promotes neuroblastoma growth through the RAS-Raf-MEK-ERK pathway
期刊论文
FEBS OPEN BIO, 2019, 卷号: 9, 期号: 3
作者:
Yan, Wangjun
;
Chen, Mo
;
Huang, Wending
;
Chang, Yong
;
Xie, Guojin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/05
apoptosis
neuroblastoma
RAS-Raf-MEK-ERK pathway
RDM1
Comprehensive genomic profiling of high-grade serous ovarian carcinoma from Chinese patients identifies co-occurring mutations in the Ras/Raf pathway with TP53
期刊论文
CANCER MEDICINE, 2019, 卷号: 8, 期号: 8
作者:
Zhong, Fangfang
;
Zhu, Tao
;
Pan, Xuedong
;
Zhang, Yanling
;
Yang, Haikun
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/12/05
comprehensive genomic profiling
high-grade serous ovarian carcinoma
KRAS
TP53
Naturally Occurring Sesquiterpene Lactone-Santonin, Exerts Anticancer Effects in Multi-Drug Resistant Breast Cancer Cells by Inducing Mitochondrial Mediated Apoptosis, Caspase Activation, Cell Cycle Arrest, and by Targeting Ras/Raf/MEK/ERK Signaling Pathway
期刊论文
MEDICAL SCIENCE MONITOR, 2019, 卷号: 25
作者:
Wu, Zhiqiang
;
Wang, Chenchen
;
Huang, Mingzhu
;
Tao, Zhonghua
;
Yan, Wangjun
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/12/05
Apoptosis
Cell Cycle
Flow Cytometry
Inflammatory Breast Neoplasms
A benzoxazole compound as a novel MEK inhibitor for the treatment of RAS/RAF mutant cancer
期刊论文
2019, 卷号: 145, 期号: 2, 页码: 586-596
作者:
Cheng, Ying
;
Wang, Xingkai
;
Xia, Xiangying
;
Zhang, Wei
;
Tian, Hongqi
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
benzoxazole compound
MEK inhibitor
RAF
RAS mutant cancer
synergism
high potency
Antiglioma via regulating oxidative stress and remodeling tumor-associated macrophage using lactoferrin-mediated biomimetic codelivery of simvastatin/fenretinide
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2018, 卷号: 287, 页码: 12-23
作者:
Mo, Xiaopeng
;
Zheng, Zening
;
He, Yang
;
Zhone, Huihai
;
Kane, Xuejia
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
Lactoferrin nanoparticle
Reactive oxygen species
Tumor-associated macrophages
Brain-targeted delivery
Biomimetic delivery
Cell penetrating peptide
Fenretinide
Simvastatin
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