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CORC

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Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing
收藏  |  浏览/下载：25/0  |  提交时间：2022/01/18
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 906, 页码: 8
作者:  Xiao, Meng-Chao;  Qian, Hui;  Huang, Chen-Kai;  Zheng, Bai-Nan;  Yan, Fang-Zhi
收藏  |  浏览/下载：50/0  |  提交时间：2021/11/04
Structural insights into ligand recognition and activation of the melanocortin-4 receptor 期刊论文
CELL RESEARCH, 2021, 页码: 13
作者:  Zhang, Huibing;  Chen, Li-Nan;  Yang, Dehua;  Mao, Chunyou;  Shen, Qingya
收藏  |  浏览/下载：34/0  |  提交时间：2021/11/04
Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 11219-11228
作者:  Zheng, Mengmeng;  Li, Chunpu;  Zhou, Mi;  Jia, Ru;  Cai, Gang
收藏  |  浏览/下载：65/0  |  提交时间：2021/11/04
PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 7, 页码: 10
作者:  Yang, Jun;  Wang, Juan;  Liu, Yuan;  Zhang, Yu;  Huang, Wenjing
收藏  |  浏览/下载：43/0  |  提交时间：2021/08/17
Mechanistic insight into morphological transition of Pluronic aggregates in aqueous solution via tuning hydrogen bonding strength 期刊论文
JOURNAL OF MOLECULAR LIQUIDS, 2021, 卷号: 333, 页码: 9
作者:  Luo, Haiyan;  Jiang, Kun;  Wang, Xiaotian;  Liang, Xiangfeng;  Liu, Huizhou
收藏  |  浏览/下载：40/0  |  提交时间：2021/08/31
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  
收藏  |  浏览/下载：74/0  |  提交时间：2021/08/17
Energy restriction causes metaphase delay and chromosome mis-segregation in cancer cells 期刊论文
CELL CYCLE, 2021, 页码: 14
作者:  Cheng, Aoxing;  Jiang, Ya;  Wang, Ting;  Yu, Fazhi;  Ishrat, Iqra
收藏  |  浏览/下载：28/0  |  提交时间：2021/12/01

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