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浏览/检索结果: 共38条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Zhang, Yong-Mei;  Ye, Lu-Yu;  Li, Tian-Yu;  Guo, Fan;  Guo, Fei 收藏  |  浏览/下载：22/0  |  提交时间：2022/01/04 YL-0919  medial prefrontal cortex  GABAergic neurons  5-HT1A receptor  GAD67-GFP transgenic mice  disinhibition  fluoxetine  electrophysiological recording   Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor 期刊论文 BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16 作者:  Yuliantie, Elita;  van der Velden, Wijnand J. C.;  Labroska, Viktorija;  Dai, Antao;  Zhao, Fenghui 收藏  |  浏览/下载：43/0  |  提交时间：2021/11/04 Glucose-dependent insulinotropic polypeptide receptor  G protein-coupled receptor  GPCR structure-function relationship  ERK  cAMP  Arrestin   Kynurenine derivative 3-HAA is an agonist ligand for transcription factor YY1 期刊论文 Journal of Hematology & Oncology, 2021, 卷号: 14, 期号: 1 作者:  Shi,Zhaopeng;  Gan,Guifang;  Xu,Xiang;  Zhang,Jieying;  Yuan,Yuan 收藏  |  浏览/下载：41/0  |  提交时间：2021/11/04 3-Hydroxyanthronic acid (3-HAA)  Kynurenine  YY1  DUSP6  Hepatocellular carcinoma (HCC)  Tryptophan metabolism   Structures of full-length glycoprotein hormone receptor signalling complexes 期刊论文 NATURE, 2021, 页码: 24 作者:  Duan, Jia;  Xu, Peiyu;  Cheng, Xi;  Mao, Chunyou;  Croll, Tristan 收藏  |  浏览/下载：53/0  |  提交时间：2021/11/04 A new approach to produce IgG(4)-like bispecific antibodies 期刊论文 SCIENTIFIC REPORTS, 2021, 卷号: 11, 期号: 1, 页码: 12 作者:  Zhao, Caizhi;  Zhang, Wei;  Gong, Guihua;  Xie, Liping;  Wang, Ming-Wei 收藏  |  浏览/下载：24/0  |  提交时间：2021/11/04 Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain 期刊论文 MOLECULAR BRAIN, 2021, 卷号: 14, 期号: 1, 页码: 22 作者:  Shao, Fang-bing;  Fang, Jun-fan;  Wang, Si-si;  Qiu, Meng-ting;  Xi, Dan-ning 收藏  |  浏览/下载：111/0  |  提交时间：2021/11/04 Chronic inflammatory pain  Anxiety-like behavior  GABAergic system  Anterior cingulate cortex  synaptic transmission   Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Wei, Yuan-yuan;  Ma, Yan;  Yao, Song-yu;  Kong, Ling-hui;  Liu, Xiao 收藏  |  浏览/下载：40/0  |  提交时间：2021/11/04 kappa-opioid receptor agonist  4,5-expoxymorphinan  antinociception  conditioned place aversion  sedation  U50,488H  morphine  Nor-BNI  beta-FNA   Structural insights into the activation of human calcium-sensing receptor 期刊论文 ELIFE, 2021, 卷号: 10, 页码: 24 作者:  Chen, Xiaochen;  Wang, Lu;  Cui, Qianqian;  Ding, Zhanyu;  Han, Li 收藏  |  浏览/下载：66/0  |  提交时间：2021/11/04 G-protein-coupled receptor  calcium-sensing receptor  cryo-electron microscopy  calcium ions  nanobody  CaSR  GPCR  cryo-EM  None   Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor 期刊论文 CELL RESEARCH, 2021, 页码: 11 作者:  Ma, Shanshan;  Chen, Yan;  Dai, Antao;  Yin, Wanchao;  Guo, Jia 收藏  |  浏览/下载：24/0  |  提交时间：2021/11/04 Signaling profiles in HEK 293T cells co-expressing GLP-1 and GIP receptors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 8 作者:  Wang, Yu-zhe;  Yang, De-hua;  Wang, Ming-wei 收藏  |  浏览/下载：20/0  |  提交时间：2021/11/04 glucagon-like peptide-1 receptor  glucose-dependent insulinotropic peptide receptor  peptide 19  LY3298176  heteromerization  type 2 diabetes