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科研机构
上海药物研究所 [8]
合肥物质科学研究院 [5]
内容类型
期刊论文 [13]
发表日期
2021 [13]
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共13条,第1-10条
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发表日期:2021
内容类型:期刊论文
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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
FK228 potentiates topotecan activity against small cell lung cancer cells via induction of SLFN11
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021
作者:
Yin, Yan-ping
;
Ma, Li-ying
;
Cao, Guo-zhen
;
Hua, Jing-han
;
Lv, Xiao-tong
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2022/01/10
small cell lung cancer
topotecan
DNA damage response
FK228
SLFN11
methylation
epigenetic modulation
Nanomedicine Strategies to Circumvent Intratumor Extracellular Matrix Barriers for Cancer Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2021, 页码: 25
作者:
Xu, Xiaoxuan
;
Wu, Yao
;
Qian, Xindi
;
Wang, Yuqi
;
Wang, Jiaoying
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/12/16
cancer therapy
drug delivery
extracellular matrix
nanomedicine
tumor penetration
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:
Jiang, Yuchen
;
Peng, Xia
;
Ji, Yinchun
;
Dai, Yang
;
Fang, Yanfen
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/16
Structural characteristics of Heparan sulfate required for the binding with the virus processing Enzyme Furin
期刊论文
GLYCOCONJUGATE JOURNAL, 2021, 页码: 11
作者:
Zeng, Jiaxin
;
Meng, Yuan
;
Chen, Shi-Yi
;
Zhao, Gaofeng
;
Wang, Lianchun
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/12/01
Furin
Heparan sulfate
Heparin
Virus infection
Carbohydrate-protein interaction
Recombinant cancer nanovaccine for targeting tumor-associated macrophage and remodeling tumor microenvironment
期刊论文
NANO TODAY, 2021, 卷号: 40, 页码: 14
作者:
Tang, Yisi
;
Fan, Wufa
;
Chen, Guihua
;
Zhang, Meng
;
Tang, Xueping
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/12/01
Cancer therapeutic vaccine
Legumain
Tumor-associated macrophage
Trichosanthin
Liposome
Adjuvant
In vitro studies of deferasirox derivatives as potential organelle-targeting traceable anti-cancer therapeutics
期刊论文
CHEMICAL COMMUNICATIONS, 2021, 页码: 4
作者:
Steinbrueck, Axel
;
Sedgwick, Adam C.
;
Han, Hai-Hao
;
Zhao, Michael Y.
;
Sen, Sajal
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/06/11
Targeting lactate dehydrogenase a improves radiotherapy efficacy in non-small cell lung cancer: from bedside to bench
期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2021, 卷号: 19
作者:
Yang, Yang
;
Chong, Yu
;
Chen, Mengyuan
;
Dai, Wumin
;
Zhou, Xia
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2021/06/15
LDHA
NSCLC
Radiosensitivity
DNA repair
ROS
Apoptosis
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
Roxithromycin attenuates bleomycin-induced pulmonary fibrosis by targeting senescent cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Xuan
;
Dong, Ying
;
Li, Wan-chen
;
Tang, Bi-xi
;
Li, Jia
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
idiopathic pulmonary fibrosis
cellular senescence
roxithromycin
NOX4
senescence-associated secretory phenotype (SASP)
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