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上海药物研究所 [24]
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期刊论文 [48]
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2020 [48]
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Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15153-15186
作者:
Zheng, Wei
;
Wang, Zhen
;
Jiang, Xiangrui
;
Zhao, Qingjie
;
Shen, Jingshan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
Drug interaction of ningetinib and gefitinib involving CYP1A1 and efflux transporters in non-small cell lung cancer patients
期刊论文
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 页码: 13
作者:
Liu, Lu
;
Wang, Qian
;
Xie, Cen
;
Xi, Ning
;
Guo, Zitao
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  |  
浏览/下载:55/0
  |  
提交时间:2020/12/24
drug–
drug interaction
gefitinib
ningetinib
transporters
Non-thermal plasma induces apoptosis accompanied by protective autophagy via activating JNK/Sestrin2 pathway
期刊论文
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2020, 卷号: 53
作者:
Ma, Jie
;
Yu, K. N.
;
Zhang, Hao
;
Nie, Lili
;
Cheng, Cheng
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  |  
浏览/下载:94/0
  |  
提交时间:2020/10/28
non-thermal plasma
apoptosis
protective autophagy
c-JUN N-terminal kinase
Sestrin2
Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2020, 卷号: 19, 期号: 11, 页码: 2340-2352
作者:
Jin, Rui
;
Liu, Liang
;
Xing, Yun
;
Meng, Tao
;
Ma, Lanping
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  |  
浏览/下载:49/0
  |  
提交时间:2020/12/24
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway
期刊论文
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:
Liu, Siwen
;
Huang, Suling
;
Wu, Xingde
;
Feng, Ying
;
Shen, Yu
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  |  
浏览/下载:55/0
  |  
提交时间:2020/12/24
Salt-inducible kinase 1
Phanginin A
Phosphodiesterase 4
Gluconeogenesis
cAMP
Oxidative damage mechanism in Saccharomyces cerevisiae cells exposed to tetrachlorobisphenol A
期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2020, 卷号: 80, 页码: 1-8
作者:
Zhang, Xiaoru
;
Zhang, Yaxian
;
Ji, Zhihua
;
Wang, Fengbang
;
Zhang, Lei
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  |  
浏览/下载:84/0
  |  
提交时间:2021/09/14
Tetrachlorobisphenol A
Reactive oxygen species accumulation
Signaling pathway
Saccharomyces cerevisiae
ULK1 inhibitor induces spindle microtubule disorganization and inhibits phosphorylation of Ser10 of histone H3
期刊论文
FEBS OPEN BIO, 2020, 卷号: 10
作者:
Ji, Xinmiao
;
Zhang, Xin
;
Li, Zhiyuan
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  |  
浏览/下载:22/0
  |  
提交时间:2020/12/07
autophagy
mitosis
MRT68921
polyploidy
SBI‐
0206965
ULK1 inhibitor
The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39
作者:
Ma, Liying
;
Bian, Xing
;
Lin, Wenchu
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/11/30
SCLC
PI3K
HDAC
CUDC-907
PARP1
Olaparib
DSB repair
Combination treatment
Efficacy of Pyrotinib in HER2-Overexpressing Salivary Duct Carcinoma With Lung Metastasis: A Case Report
期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Yang, Zi-yan
;
Huang, Jia-huan
;
Chen, Bo
;
Xu, Chun-wei
;
Lei, Lei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/11/30
salivary duct carcinoma
tyrosine kinase inhibitor
pyrotinib
HER2 positive
targeted
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